Virulence factors of uropathogenic Escherichia coli of urinary tract infections and asymptomatic bacteriuria in children
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Yun, Ki Wook | - |
dc.contributor.author | Kim, Hak Young | - |
dc.contributor.author | Park, Hee Kuk | - |
dc.contributor.author | Kim, Wonyong | - |
dc.contributor.author | Lim, In Seok | - |
dc.date.available | 2019-03-08T20:41:28Z | - |
dc.date.issued | 2014-12 | - |
dc.identifier.issn | 1684-1182 | - |
dc.identifier.issn | 1995-9133 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/11528 | - |
dc.description.abstract | Background/Purpose: The clinical aspects of virulence genes of uropathogenic Escherichia coli (UPEC) are not fully understood. This study compared the presence of virulence genes in UPEC isolated from urinary tract infections (UTIs) and asymptomatic bacteriuria (ABU) in children. Methods: The study included children with UTI (n = 15) or ABU (n = 49) treated at Chung-Ang University Yongsan Hospital between 2010 and 2011. The strains were acquired from each urine sample collected, and 18 major virulence genes were detected by polymerase chain reaction. Antimicrobial susceptibility of all UPEC isolates was determined. Results: Sixty-four E. coli strains were isolated from the urine samples. The most commonly identified virulence gene in both groups was fimH (100.0% in the UTI group and 95.9% in the ABU group). The UTI isolates showed a higher prevalence of papEF and fyuA, and a lower prevalence of feoB than ABU isolates (p < 0.01 for all). The profile of virulence gene, fimH (|) kpsMTII (|) feoB(|) also showed a significant difference between the two groups (p < 0.01). Isolates from ABU were more resistant to most antimicrobials tested. The presence of papEF, feoB, and fyuA also correlated with the antimicrobial susceptibility of UPEC. Conclusion: The virulence gene repertoire was different in the UPEC of UTI and ABU. The papEF, feoB, and fyuA genes showed meaningful differences between the two groups and may have an important role in the pathogenesis of overt UTI. Copyright (C) 2013, Taiwan Society of Microbiology. Published by Elsevier Taiwan LLC. All rights reserved. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER TAIWAN | - |
dc.title | Virulence factors of uropathogenic Escherichia coli of urinary tract infections and asymptomatic bacteriuria in children | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.jmii.2013.07.010 | - |
dc.identifier.bibliographicCitation | JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION, v.47, no.6, pp 455 - 461 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000345561300002 | - |
dc.identifier.scopusid | 2-s2.0-84908572622 | - |
dc.citation.endPage | 461 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 455 | - |
dc.citation.title | JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION | - |
dc.citation.volume | 47 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대만 | - |
dc.subject.keywordAuthor | Asymptomatic bacteriuria | - |
dc.subject.keywordAuthor | Urinary tract infection | - |
dc.subject.keywordAuthor | Uropathogenic Escherichia coli | - |
dc.subject.keywordAuthor | Virulence genes | - |
dc.subject.keywordPlus | ACUTE LOBAR NEPHRONIA | - |
dc.subject.keywordPlus | POLYMERASE-CHAIN-REACTION | - |
dc.subject.keywordPlus | PATHOGENICITY ISLAND | - |
dc.subject.keywordPlus | ACUTE PYELONEPHRITIS | - |
dc.subject.keywordPlus | UROVIRULENCE FACTORS | - |
dc.subject.keywordPlus | YOUNG-WOMEN | - |
dc.subject.keywordPlus | STRAINS | - |
dc.subject.keywordPlus | UROSEPSIS | - |
dc.subject.keywordPlus | RESISTANCE | - |
dc.subject.keywordPlus | GENOTYPES | - |
dc.relation.journalResearchArea | Immunology | - |
dc.relation.journalResearchArea | Infectious Diseases | - |
dc.relation.journalResearchArea | Microbiology | - |
dc.relation.journalWebOfScienceCategory | Immunology | - |
dc.relation.journalWebOfScienceCategory | Infectious Diseases | - |
dc.relation.journalWebOfScienceCategory | Microbiology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.