The impact of medication adherence on health outcomes for chronic metabolic diseases: A retrospective cohort study
DC Field | Value | Language |
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dc.contributor.author | Han, Euna | - |
dc.contributor.author | Suh, Dong-Churl | - |
dc.contributor.author | Lee, Seung-Mi | - |
dc.contributor.author | Jang, Sunmee | - |
dc.date.available | 2019-03-08T20:57:57Z | - |
dc.date.issued | 2014-11 | - |
dc.identifier.issn | 1551-7411 | - |
dc.identifier.issn | 1934-8150 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/11668 | - |
dc.description.abstract | Background: Hypertension, diabetes, and hyperlipidemia have a large influence on health outcomes due to their chronic nature and serious complications. Medication is a key factor in preventing disease advancement, and it is important to assess whether good medication adherence has any potential long-term impact on health outcomes and provides an international validation on the relationship. Objectives: To evaluate the impact of good medication adherence on health outcomes of complications and hospitalizations for hypertension, hyperlipidemia, and diabetes. Methods: Patients who had had outpatient pharmacy claims for drugs for hypertension, diabetes, or hyperlipidemia were separately identified from the Korean National Health Insurance Claims Database in year 2009. A 10% random sample was respectively drawn from the three disease groups, and all claims from years 2008-2011 were extracted for the sampled subjects. Medication adherence was measured by the medication possession ratio (MPR) during the 12-month after the index date, the initial date from when medication was counted, with poor adherence as <80% of MPR. Health outcomes were measured both at 2 and 3 years after the index date as any occurrence of disease-related complications, disease-specific hospitalizations, and all-cause hospitalizations. Results: Poor medication adherence was associated with a higher occurrence of disease-specific hospitalizations for hypertension patients (+10.9%, only at 2 years). The likelihood of all-cause hospitalization was higher among patients who had poor medication adherence in hypertension (+32% and +29% at 2 and 3 years), hyperlipidemia (+16% and +14% at 2 and 3 years), and diabetes (+32% and +29% at 2 and 3 years). Poor medication adherence also increased the likelihood of complications for hypertension (+14% and +7% at 2 and 3 years) and hyperlipidemia patients (+8.1% at 2 years). Conclusions: Targeting good medication adherence could be a valuable policy strategy to effectively manage chronic diseases to improve health outcomes. (C) 2014 Elsevier Inc. All rights reserved. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER SCIENCE INC | - |
dc.title | The impact of medication adherence on health outcomes for chronic metabolic diseases: A retrospective cohort study | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.sapharm.2014.02.001 | - |
dc.identifier.bibliographicCitation | RESEARCH IN SOCIAL & ADMINISTRATIVE PHARMACY, v.10, no.6, pp E87 - E98 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000345388400002 | - |
dc.identifier.scopusid | 2-s2.0-84923013699 | - |
dc.citation.endPage | E98 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | E87 | - |
dc.citation.title | RESEARCH IN SOCIAL & ADMINISTRATIVE PHARMACY | - |
dc.citation.volume | 10 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | Medication adherence | - |
dc.subject.keywordAuthor | Health outcomes | - |
dc.subject.keywordAuthor | Hypertension | - |
dc.subject.keywordAuthor | Diabetes | - |
dc.subject.keywordAuthor | Hyperlipidemia | - |
dc.subject.keywordAuthor | National health insurance claims data | - |
dc.subject.keywordAuthor | South Korea | - |
dc.subject.keywordPlus | BLOOD-PRESSURE CONTROL | - |
dc.subject.keywordPlus | MAINTENANCE ORGANIZATION | - |
dc.subject.keywordPlus | HOSPITALIZATION RISK | - |
dc.subject.keywordPlus | STATIN TREATMENT | - |
dc.subject.keywordPlus | PERSISTENCE | - |
dc.subject.keywordPlus | HYPERTENSION | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | POPULATION | - |
dc.subject.keywordPlus | DRUGS | - |
dc.relation.journalResearchArea | Public, Environmental & Occupational Health | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalWebOfScienceCategory | Public, Environmental & Occupational Health | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.description.journalRegisteredClass | ssci | - |
dc.description.journalRegisteredClass | scopus | - |
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