Microencapsulation by pectin for multi-components carriers bearing both hydrophobic and hydrophilic active agents
- Authors
- Noh, Juran; Kim, Jin; Kim, Jin Sic; Chung, Young Soo; Chang, Suk Tai; Park, Juhyun
- Issue Date
- Feb-2018
- Publisher
- ELSEVIER SCI LTD
- Keywords
- Citrus pectin; Micro-encapsulation; Multi-component cosmetic carrier; Ionic cross-linking; Microfluidic system
- Citation
- CARBOHYDRATE POLYMERS, v.182, pp 172 - 179
- Pages
- 8
- Journal Title
- CARBOHYDRATE POLYMERS
- Volume
- 182
- Start Page
- 172
- End Page
- 179
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/1186
- DOI
- 10.1016/j.carbpol.2017.11.026
- ISSN
- 0144-8617
1879-1344
- Abstract
- Oil/water microencapsulation by microfluidic systems has been a prominent delivery method to prepare functional microcapsules in the food, cosmetic, and pharmaceutical industries because it is an easy way to control the shape and size of structures and functionalities. We prepared biocompatible and multi-component microcapsules using the precipitation and ionic crosslinking of pectin in a poor solubility environment and with multivalent cations, respectively. When the aqueous solution (including calcium ions and ethanol) in a sheath flow met the flow of a pectin aqueous solution containing oil droplets, ethanol-gelation and ionic cross-linking occurred, enclosing the inner oil phase droplets by solidified pectin shells. Furthermore, the resulting microcapsules stabilized by pectin shells exhibited functionalities using a hydrophobic agent and nanoparticles of a hydrophilic species that were dissolved and dispersed, respectively, in the oil phase.
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Collections - College of Engineering > School of Chemical Engineering and Material Science > 1. Journal Articles
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