Feasibility of blood oxygenation level-dependent MRI at 3T in the characterization of hepatic tumors
DC Field | Value | Language |
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dc.contributor.author | Park, Hyun Jeong | - |
dc.contributor.author | Kim, Young Kon | - |
dc.contributor.author | Min, Ji Hye | - |
dc.contributor.author | Lee, Won Jae | - |
dc.contributor.author | Choi, Dongil | - |
dc.contributor.author | Rhim, Hyunchul | - |
dc.date.available | 2019-03-08T22:37:02Z | - |
dc.date.issued | 2014-02 | - |
dc.identifier.issn | 0942-8925 | - |
dc.identifier.issn | 1432-0509 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/12516 | - |
dc.description.abstract | To determine the feasibility of using blood oxygenation level-dependent (BOLD) MRI in the characterization of hepatic tumors. A total of 100 patients with 43 hepatocellular carcinomas (HCCs), 36 metastases, 17 cholangiocarcinomas, and 23 hemangiomas underwent gadoxetic acid-enhanced and BOLD MRI at 3T. BOLD MRI was performed using a multiple fast-field echo sequence (TR/TE, 290/10-28; slice thickness 5 mm) to generate 20 T2*-weighted images. The T2* value of each tumor were calculated. On a color-coded T2* map, tumors were classified into five categories of high signal intensity (strong, moderate, rim, mild) and iso-intensity, which was correlated with the enhancement pattern on dynamic phases by two observers. The mean T2* value (ms) of hemangiomas (97.3 +/- A 20.2) was the highest, followed by HCCs (48.4 +/- A 12.7), metastases (37.1 +/- A 10.5), and cholangiocarcinomas (36.6 +/- A 11.1). These values were significantly different (hemangioma vs. others tumors and HCC vs. metastasis or cholangiocarcinoma) (P a parts per thousand currency sign 0.001). The agreement between the T2* color map and dynamic images was moderate for all tumors (k = 0.544), good for tumors > 2.0 cm (k = 0.666), and fair for tumors a parts per thousand currency sign2.0 cm (k = 0.334). With the gadoxetic acid-enhanced MRI used as a reference, the sensitivities of BOLD MRI (T2* color map) for displaying hypervascularity of HCC (categories of 1-3) were 81.0 % (n = 34/42) and 78.6 % (n = 33/42) for both observers. Liver BOLD MRI has a potential to predict the vascular pattern of hepatic tumors. | - |
dc.format.extent | 11 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | SPRINGER | - |
dc.title | Feasibility of blood oxygenation level-dependent MRI at 3T in the characterization of hepatic tumors | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s00261-013-0044-2 | - |
dc.identifier.bibliographicCitation | ABDOMINAL IMAGING, v.39, no.1, pp 142 - 152 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000330728900013 | - |
dc.identifier.scopusid | 2-s2.0-84897652474 | - |
dc.citation.endPage | 152 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 142 | - |
dc.citation.title | ABDOMINAL IMAGING | - |
dc.citation.volume | 39 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | Blood oxygenation level-dependent | - |
dc.subject.keywordAuthor | T2*mapping | - |
dc.subject.keywordAuthor | Liver tumors | - |
dc.subject.keywordAuthor | Magnetic resonance imaging | - |
dc.subject.keywordPlus | PROSTATE-CANCER | - |
dc.subject.keywordPlus | CONTRAST | - |
dc.subject.keywordPlus | HYPOXIA | - |
dc.subject.keywordPlus | FIBROSIS | - |
dc.subject.keywordPlus | BREAST | - |
dc.subject.keywordPlus | BRAIN | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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