한국형 양극성 장애 약물치료 알고리듬 2014: 안정성과 내약성
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 손인기 | - |
dc.contributor.author | 김문두 | - |
dc.contributor.author | 이정구 | - |
dc.contributor.author | 윤보현 | - |
dc.contributor.author | 정종현 | - |
dc.contributor.author | 심세훈 | - |
dc.contributor.author | 우영섭 | - |
dc.contributor.author | 서정석 | - |
dc.contributor.author | 신영철 | - |
dc.contributor.author | 민경준 | - |
dc.contributor.author | 박원명 | - |
dc.contributor.author | 전덕인 | - |
dc.date.available | 2019-03-08T22:41:05Z | - |
dc.date.issued | 2014 | - |
dc.identifier.issn | 1017-5717 | - |
dc.identifier.issn | 2092-5700 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/12702 | - |
dc.description.abstract | 양극성 장애는 질환 자체의 신체질환 공존 위험성과 여러 치료 약물의 부작용의 가능성 때문에 치료 전략과 약물 선택에 고도의 전문가적 판단이 요구된다. 저자들은 다양한 임상 상황에서 전문가들의 의견을 조사하여 임상 진료에 도움이 되고자 하였다. 체중증가, 항정신병약물 관련 고프로락틴혈증, lamotrigine 관련 피부발진, 치료 비순응과 유전상담의 상황에 대하여 64명의 전문가들에게 설문 조사를 시행하였다. 이 설문조사를 바탕으로 한국판 양극성 장애 약물치료 알고리듬 2014를 제작하였다. 본 연구가 다루었던 임상 상황들에 대한 임상연구나 치료지침은 양극성 장애의 다른 상황에 대한 것들보다 상대적으로 부족하다. 그러므로 본 치료지침에 대한 연구의 결과는 임상가의 경험과 개별 환자의 고유한 상황에 맞추어 적용되어야 한다. | - |
dc.description.abstract | Objective: The complexity of the treatment for bipolar disorder is often caused by the presence of side effects of various psychiatric medications. In particular, weight gain and metabolic syndrome are currently major concerns in the medication for bipolar disorders. Therefore, we undertook a survey of expert opinion to help make clinical decisions in these special situations. Methods: A written survey which asked about treatment strategies in the safety and tolerability was prepared; 1) weight gain, 2) antipsychotic related hyperprolactinemia, 3) lamotrigine related skin rash, 4) treatment non-adherence, and 5) genetic counselling. Treatment options were scored using a 9-point scale for rating appropriateness of clinical decisions in some issues. In other issues, experts were asked to choose to determine the ranking of preferences on the list. Sixty-four experts of the review committee completed the survey. We classified the expert opinions about preferences by χ2 test. Results: Experts preferred behavioral and diet modification for weight gain, switching to prolactin-sparing-antipsychotics for antipsychotic-induced hyperprolactinemia, reducing dose of lamotrigene for its related benign skin rash, and prescribing once a day for treatment adherence. Conclusion: With the limitation of expert opinion, authors hope that the results of this study provide valuable information to make clinical decision about the treatment of bipolar disorder in the complicated situations. | - |
dc.format.extent | 7 | - |
dc.publisher | 대한정신약물학회 | - |
dc.title | 한국형 양극성 장애 약물치료 알고리듬 2014: 안정성과 내약성 | - |
dc.title.alternative | Korean Medication Algorithm for Bipolar Disorder 2014: Safety and Tolerability | - |
dc.type | Article | - |
dc.identifier.bibliographicCitation | 대한정신약물학회지, v.25, no.4, pp 161 - 167 | - |
dc.identifier.kciid | ART001924350 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | 167 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 161 | - |
dc.citation.title | 대한정신약물학회지 | - |
dc.citation.volume | 25 | - |
dc.identifier.url | http://www.riss.kr/search/detail/DetailView.do?p_mat_type=1a0202e37d52c72d&control_no=f1baa07f86d67bb1e9810257f7042666 | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | 양극성 장애 | - |
dc.subject.keywordAuthor | 체중증가 | - |
dc.subject.keywordAuthor | 비순응 | - |
dc.subject.keywordAuthor | 고프로락틴혈증 | - |
dc.subject.keywordAuthor | 유전상담 | - |
dc.subject.keywordAuthor | 알고리듬 | - |
dc.subject.keywordAuthor | Bipolar disorder | - |
dc.subject.keywordAuthor | Weight gain | - |
dc.subject.keywordAuthor | Non-adherence | - |
dc.subject.keywordAuthor | Lamotrigine | - |
dc.subject.keywordAuthor | Hyperprolactinemia | - |
dc.subject.keywordAuthor | Genetic counselling | - |
dc.subject.keywordAuthor | Algorithm | - |
dc.description.journalRegisteredClass | kci | - |
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