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신이식 후 거대세포바이러스 감염을 동반한 감염성 심내막염 1예open accessA Case of Infective Endocarditis with Cytomegalovirus Infection after Kidney Transplantation

Authors
홍문기김도형김채림홍준화김미경김수현
Issue Date
May-2014
Publisher
대한내과학회
Keywords
Aspergillus; Cytomegalovirus; Endocarditis; Kidney transplantation; 아스페르길루스; 거대세포바이러스; 감염성 심내막염; 신장이식
Citation
대한내과학회지, v.86, no.5, pp 627 - 631
Pages
5
Journal Title
대한내과학회지
Volume
86
Number
5
Start Page
627
End Page
631
URI
https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/13457
DOI
10.3904/kjm.2014.86.5.627
ISSN
1738-9364
2289-0769
Abstract
저자들은 신장이식 후 면역억제제를 지속적으로 사용하는 환자에서 거대세포바이러스 감염과 함께 병발한 아스페르길루스 심내막염 1예를 경험하였다. 최근 면역억제제 사 용이 증가하면서 면역 저하와 함께 기회 감염의 빈도도 증가하고 있으며 특히 거대세포바이러스 감염을 동반할 경우 면역 억제의 정도가 심해지면서 그 빈도가 더욱 증가할 것 으로 생각된다. 특히 아스페르길루스와 같은 진균 감염의 경우 혈액배양 검사에서 동정될 확률이 낮고 치료 시기를 놓칠 경우 사망률이 높음으로 기회 감염에 대한 혈청학적 검사가 진단 및 치료에 중요한 단서가 될 수 있다.
Advances in immunosuppressive therapy have increased the survival of kidney transplant recipients, yet suppression of the immunesystem after transplantation can promote infectious complications. Cytomegalovirus (CMV) infection remains one of themost important complications following kidney transplantation and it is a risk factor for developing superinfections with otherorganisms. Aspergillus endocarditis is a rare life‐threatening complication in kidney transplantation. Coinfection of CMV andAspergillus endocarditis is rare worldwide and has not been reported in Korea. We report a case of Aspergillus endocarditis that developedin a patient with CMV infection after kidney transplantation. His clinical condition did not improve despite mitral valve replacementand empirical antibiotic treatment, but he was eventually treated successfully with antifungal agents for 6 weeks.
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의과대학 (의학부(임상-광명))
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