The role of diffusion-weighted MR imaging for differentiating benign from malignant bile duct strictures
DC Field | Value | Language |
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dc.contributor.author | Park, H.J. | - |
dc.contributor.author | Kim, S.H. | - |
dc.contributor.author | Jang, K.M. | - |
dc.contributor.author | Choi, S.-Y. | - |
dc.contributor.author | Lee, S.J. | - |
dc.contributor.author | Choi, D. | - |
dc.date.available | 2019-03-09T00:39:15Z | - |
dc.date.issued | 2014-04 | - |
dc.identifier.issn | 0938-7994 | - |
dc.identifier.issn | 1432-1084 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/13819 | - |
dc.description.abstract | Objectives: To assess the added value of diffusion-weighted imaging (DWI) to conventional magnetic resonance imaging (MRI) for differentiating benign from malignant bile duct strictures. Methods: Twenty-seven patients with a benign stricture and 42 patients with a malignant stricture who had undergone gadoxetic acid-enhanced MRI with DWI were enrolled. Qualitative (signal intensity, dynamic enhancement pattern) and quantitative (wall thickness and length) analyses were performed. Two observers independently reviewed a set of conventional MRI and a combined set of conventional MRI and DWI, and receiver operating characteristic (ROC) curve analysis was assessed. Results: Benign strictures showed isointensity (18.5-70.4 %) and a similar enhancement pattern (22.2 %) to that of normal bile duct more frequently than malignant strictures (0-40.5 % and 0 %) on conventional MRI (P<0.05). Malignant strictures (90.5-92.9 %) showed hypervascularity on arterial and portal venous phase images more frequently than benign strictures (37.0-70.4 %) (P<0.01) On DWI, all malignant strictures showed hyperintensity compared with benign cases (70.4 %) (P<0.001). Malignant strictures were significantly thicker and longer than benign strictures (P<0.001). The diagnostic performance of both observers improved significantly after additional review of DWI. Conclusions: Adding DWI to conventional MRI is more helpful for differentiating benign from malignant bile duct strictures than conventional MRI alone. Key points: • Accurate diagnosis and exclusion of benign strictures of bile duct are important. • Diffusion-weighted MRI helps to distinguish benign from malignant bile duct strictures. • DWI plus conventional MRI provides superior diagnostic accuracy to conventional MRI alone. © 2014 European Society of Radiology. | - |
dc.format.extent | 12 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Springer Verlag | - |
dc.title | The role of diffusion-weighted MR imaging for differentiating benign from malignant bile duct strictures | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s00330-014-3097-x | - |
dc.identifier.bibliographicCitation | European Radiology, v.24, no.4, pp 947 - 958 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000332658400022 | - |
dc.identifier.scopusid | 2-s2.0-84896318654 | - |
dc.citation.endPage | 958 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 947 | - |
dc.citation.title | European Radiology | - |
dc.citation.volume | 24 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | Bile duct stricture | - |
dc.subject.keywordAuthor | Cholangiocarcinoma | - |
dc.subject.keywordAuthor | Diffusion-weighted imaging | - |
dc.subject.keywordAuthor | Gadoxetic acid | - |
dc.subject.keywordAuthor | Magnetic resonance imaging | - |
dc.relation.journalResearchArea | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.relation.journalWebOfScienceCategory | Radiology, Nuclear Medicine & Medical Imaging | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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