The Clinical Impact of the Sum of the Maximum Standardized Uptake Value on the Pretreatment with F-18-FDG-PET/CT in Small-Cell Lung Cancer
DC Field | Value | Language |
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dc.contributor.author | Go, Se-Il | - |
dc.contributor.author | Song, Haa-Na | - |
dc.contributor.author | Kang, Jung-Hun | - |
dc.contributor.author | Kang, Myung Hee | - |
dc.contributor.author | Kim, Moon Jin | - |
dc.contributor.author | Jung, Jaehoon | - |
dc.contributor.author | Chung, Soon Il | - |
dc.contributor.author | Choi, Bong-Hoi | - |
dc.contributor.author | Hwang, In-Gyu | - |
dc.contributor.author | Kim, Seok-Hyun | - |
dc.contributor.author | Ling, Hui | - |
dc.contributor.author | Lee, Gyeong-Won | - |
dc.date.available | 2019-03-09T00:41:37Z | - |
dc.date.issued | 2014-01 | - |
dc.identifier.issn | 0030-2414 | - |
dc.identifier.issn | 1423-0232 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/13909 | - |
dc.description.abstract | Objectives: The aim of this study was to investigate the clinical significance of the sum of the maximum standardized uptake value (sumSUV(max)) on pretreatment positron emission tomography/computed tomography (F-18-FDG-PET/CT) in newly diagnosed small-cell lung cancer (SCLC). Methods: We retrospectively analyzed 145 SCLC patients from March 2005 to June 2013 who underwent pretreatment F-18-FDG-PET/CT. The sumSUV(max) was assessed in all malignant lesions up to a maximum of 5 lesions and a maximum of 2 lesions per organ according to RECIST 1.1. Results: A significant difference was found between the low and high sumSUV(max) groups (low vs. high sumSUV(max), 91.5 vs. 77.3%; p = 0.018) in the response rate (RR) following frontline platinum-based chemotherapy. The group with low sumSUV(max) showed significantly better overall survival (OS; p < 0.001) as well as better progression-free survival (PFS; p < 0.001) compared with the group with high sumSUV(max). Moreover, multivariate analysis revealed that a high sumSUV(max) alone was an independent poor prognostic factor for OS (hazard ratio 2.676; 95% confidence interval, 1.674-4.277; p < 0.001). Conclusions: This study showed that the sumSUV(max) adopted from RECIST 1.1 on pretreatment F-18-FDG PET/CT was significantly correlated with response to treatment, OS, and PFS in patients with SCLC. (C) 2013 S. Karger AG, Basel | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | KARGER | - |
dc.title | The Clinical Impact of the Sum of the Maximum Standardized Uptake Value on the Pretreatment with F-18-FDG-PET/CT in Small-Cell Lung Cancer | - |
dc.type | Article | - |
dc.identifier.doi | 10.1159/000357136 | - |
dc.identifier.bibliographicCitation | ONCOLOGY, v.86, no.1, pp 1 - 9 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000329924100001 | - |
dc.identifier.scopusid | 2-s2.0-84893109994 | - |
dc.citation.endPage | 9 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 1 | - |
dc.citation.title | ONCOLOGY | - |
dc.citation.volume | 86 | - |
dc.type.docType | Article | - |
dc.publisher.location | 스위스 | - |
dc.subject.keywordAuthor | Platinum | - |
dc.subject.keywordAuthor | Positron emission tomography | - |
dc.subject.keywordAuthor | Small-cell lung carcinoma | - |
dc.subject.keywordAuthor | Survival | - |
dc.subject.keywordPlus | POSITRON-EMISSION-TOMOGRAPHY | - |
dc.subject.keywordPlus | PROGNOSTIC-FACTORS | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | DISEASE | - |
dc.subject.keywordPlus | PET/CT | - |
dc.subject.keywordPlus | PREDICTION | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.subject.keywordPlus | SURGERY | - |
dc.subject.keywordPlus | CT | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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