Anti-oxidative and anti-inflammatory activities of caffeoyl hemiterpene glycosides from Spiraea prunifolia
DC Field | Value | Language |
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dc.contributor.author | Park, Sang Hee | - |
dc.contributor.author | Park, Kwan Hee | - |
dc.contributor.author | Oh, Myeong Hwan | - |
dc.contributor.author | Kim, Han Hyuk | - |
dc.contributor.author | Choe, Kang In | - |
dc.contributor.author | Kim, So Ra | - |
dc.contributor.author | Park, Kwang Jun | - |
dc.contributor.author | Lee, Min Won | - |
dc.date.available | 2019-03-09T00:58:58Z | - |
dc.date.issued | 2013-12 | - |
dc.identifier.issn | 0031-9422 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/14101 | - |
dc.description.abstract | Activity guided isolation of a Spiraea prunifolia extract yielded five caffeoyl hemiterpene glycosides: 4'-(6-O-caffeoyl-beta-D-glucopyranosyl)-2'-methyl butyric acid, 1-O-caffeoyl-6-O-(4'-hydroxy-2'-methylene-butyroyl)-beta-D-glucopyranoside, 1,2-O-dicaffeoyl-6-O-(4'-hydroxy-2'-methylene-butyroyl)-beta-D-glucopyranoside, 1-O-caffeoyl-6-O-(4'-caffeoyl-2'-methylene-butyroyl)-beta-D-glucopyranoside, and 1-O-caffeoyl-6-O-(4'-caffeoyl-3'-hydroxy-2'-methylene-butyroyl)-beta-D-glucopyranoside, and nine known compounds. Structures were elucidated by analysis of 1D and 2D NMR spectra and FAB-MS. To evaluate the anti-oxidative and anti-inflammatory properties of all fourteen compounds, DPPH radical scavenging, NBT superoxide scavenging, and inhibition of nitric oxide production in LPS-stimulated RAW264.7 cells were examined. Three of the caffeoyl hemiterpene glycosides exhibited potent anti-oxidative and anti-inflammatory activities compared with Vitamin C and L-NMMA, which were used as positive controls. (C) 2013 Published by Elsevier Ltd. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
dc.title | Anti-oxidative and anti-inflammatory activities of caffeoyl hemiterpene glycosides from Spiraea prunifolia | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.phytochem.2013.09.017 | - |
dc.identifier.bibliographicCitation | PHYTOCHEMISTRY, v.96, pp 430 - 436 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000328869500046 | - |
dc.identifier.scopusid | 2-s2.0-84888378224 | - |
dc.citation.endPage | 436 | - |
dc.citation.startPage | 430 | - |
dc.citation.title | PHYTOCHEMISTRY | - |
dc.citation.volume | 96 | - |
dc.type.docType | Article | - |
dc.publisher.location | 영국 | - |
dc.subject.keywordAuthor | Spiraea prunifolia | - |
dc.subject.keywordAuthor | Rosaceae | - |
dc.subject.keywordAuthor | Caffeoyl hemiterpenes | - |
dc.subject.keywordAuthor | Hemiterpene glycosides | - |
dc.subject.keywordAuthor | DPPH radical scavenging activity | - |
dc.subject.keywordAuthor | NBT superoxide scavenging activity | - |
dc.subject.keywordAuthor | NO production | - |
dc.subject.keywordPlus | RAW 264.7 CELLS | - |
dc.subject.keywordPlus | NITRIC-OXIDE | - |
dc.subject.keywordPlus | ALSTROEMERIA-REVOLUTA | - |
dc.subject.keywordPlus | GLUCOSIDES | - |
dc.subject.keywordPlus | TULIPOSIDES | - |
dc.subject.keywordPlus | QUANTIFICATION | - |
dc.subject.keywordPlus | CONSTITUENTS | - |
dc.subject.keywordPlus | SUPEROXIDE | - |
dc.subject.keywordPlus | EXTRACT | - |
dc.subject.keywordPlus | TANNINS | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Plant Sciences | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Plant Sciences | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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