Familial Occurrence of Pulmonary Embolism after Intravenous, Adipose Tissue-Derived Stem Cell Therapy
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Jung, Jae Woo | - |
dc.contributor.author | Kwon, Minsuk | - |
dc.contributor.author | Choi, Jae Chol | - |
dc.contributor.author | Shin, Jong Wook | - |
dc.contributor.author | Park, In Won | - |
dc.contributor.author | Choi, Byoung Whui | - |
dc.contributor.author | Kim, Jae Yeol | - |
dc.date.available | 2019-03-09T01:37:10Z | - |
dc.date.issued | 2013-09 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.issn | 1976-2437 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/14314 | - |
dc.description.abstract | The therapeutic potential of human multipotent mesenchymal stromal cells, especially human adipose tissue-derived stem cells (hASC), is promising. However, there are concerns about the safety of infusion of hASC in human. Recently, we have experienced pulmonary embolism and infarct among family members who have taken multiple infusions of intravenous autologous hASC therapy. A 41-year-old man presented with chest pain for one month. Chest CT showed multiple pulmonary artery embolism and infarct at right lung. Serum D-dimer was 0.8 mu g/mL (normal; 0-0.5 mu g/mL). He had received intravenous autologous adipose tissue-derived stem cell therapy for cervical herniated intervertebral disc three times (one, two, and three months prior to the visit). His parents also received the same therapy five times and their chest CT also showed multiple pulmonary embolism. These cases represent artificial pulmonary embolisms and infarct after IV injection of hASC. Follow-up chest CT showed spontaneous resolution of lesions in all three patients. | - |
dc.format.extent | 4 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | YONSEI UNIV COLL MEDICINE | - |
dc.title | Familial Occurrence of Pulmonary Embolism after Intravenous, Adipose Tissue-Derived Stem Cell Therapy | - |
dc.type | Article | - |
dc.identifier.doi | 10.3349/ymj.2013.54.5.1293 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, v.54, no.5, pp 1293 - 1296 | - |
dc.identifier.kciid | ART001794725 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000326128500032 | - |
dc.identifier.scopusid | 2-s2.0-84880995262 | - |
dc.citation.endPage | 1296 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 1293 | - |
dc.citation.title | YONSEI MEDICAL JOURNAL | - |
dc.citation.volume | 54 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Stem cell | - |
dc.subject.keywordAuthor | pulmonary embolism | - |
dc.subject.keywordAuthor | infarct | - |
dc.subject.keywordAuthor | family | - |
dc.subject.keywordPlus | MESENCHYMAL STEM | - |
dc.subject.keywordPlus | STROMAL CELLS | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.