Anti-oxidative and Anti-inflammatory Effects of Flavonoids from the Silk of Zea mays Linn
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Oh, M. H. | - |
dc.contributor.author | Choe, K. I. | - |
dc.contributor.author | Cho, S. H. | - |
dc.contributor.author | Jeong, M. S. | - |
dc.contributor.author | Myung, S. C. | - |
dc.contributor.author | Seo, S. J. | - |
dc.contributor.author | Choi, S. E. | - |
dc.contributor.author | Lee, M. W. | - |
dc.date.available | 2019-03-09T01:41:11Z | - |
dc.date.issued | 2013-07 | - |
dc.identifier.issn | 0970-7077 | - |
dc.identifier.issn | 0975-427X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/14483 | - |
dc.description.abstract | Activity-guided isolation of the silk of Zea mays Linn (ZMS) yielded three flavonoids, chrysoeriol-6-C-beta-boivinopyranosyl-7-O-beta-glucopyranoside (1), chrysoeriol (2) and luteolin (3). Anti-oxidative activity was measured using the 2,2-diphenyl-1-picryl-hydrazyl and superoxide dismutase-like superoxide anion (generated by xanthine oxidase/hypoxanthine) scavenging assays. Anti-inflammatory activity was confined by quantifying the protein and mRNA levels of inducible nitric oxide synthase and cyclooxygenase-2 in lipopolysaccharide-stimulated HaCaT cells using western blotting and real-time polymerase chain reaction. The results showed that luteolin 3 exhibited potent 2,2-diphenyl-1-picryl-hydrazyl (IC50 = 18.31 +/- 1.29 mu M) and superoxide dismutase-like superoxide anion scavenging activity (IC50 = 1.47 +/- 0.14 mu M) and dose-dependently inhibited the protein expression of inducible nitric oxide synthase and cyclooxygenase-2 as well as their mRNA levels. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ASIAN JOURNAL OF CHEMISTRY | - |
dc.title | Anti-oxidative and Anti-inflammatory Effects of Flavonoids from the Silk of Zea mays Linn | - |
dc.type | Article | - |
dc.identifier.doi | 10.14233/ajchem.2013.13943 | - |
dc.identifier.bibliographicCitation | ASIAN JOURNAL OF CHEMISTRY, v.25, no.8, pp 4293 - 4297 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000317246400037 | - |
dc.identifier.scopusid | 2-s2.0-84877279454 | - |
dc.citation.endPage | 4297 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 4293 | - |
dc.citation.title | ASIAN JOURNAL OF CHEMISTRY | - |
dc.citation.volume | 25 | - |
dc.type.docType | Article | - |
dc.publisher.location | 인도 | - |
dc.subject.keywordAuthor | Zea mays Linn | - |
dc.subject.keywordAuthor | Flavonoid | - |
dc.subject.keywordAuthor | Anti-oxidative | - |
dc.subject.keywordAuthor | Anti-inflammatory | - |
dc.subject.keywordAuthor | Inducible nitric oxide synthase | - |
dc.subject.keywordAuthor | Cyclooxygenase-2 | - |
dc.subject.keywordPlus | GLYCATION INHIBITORY-ACTIVITY | - |
dc.subject.keywordPlus | MAYDIS-STIGMA EXTRACTS | - |
dc.subject.keywordPlus | NITRIC-OXIDE SYNTHASE | - |
dc.subject.keywordPlus | CORN SILK | - |
dc.subject.keywordPlus | CYCLOOXYGENASE | - |
dc.subject.keywordPlus | GLYCOSIDES | - |
dc.subject.keywordPlus | STYLE | - |
dc.subject.keywordPlus | L. | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.