Is progressive upper-body apraxia a corticobasal syndrome?
- Authors
- Shin, Hae-Won; Song, Sook-Keun; Sohn, Young H.
- Issue Date
- Feb-2013
- Publisher
- ELSEVIER SCI LTD
- Keywords
- Corticobasal degeneration; Focal cortical atrophy; Upper-body apraxia
- Citation
- JOURNAL OF CLINICAL NEUROSCIENCE, v.20, no.2, pp 313 - 316
- Pages
- 4
- Journal Title
- JOURNAL OF CLINICAL NEUROSCIENCE
- Volume
- 20
- Number
- 2
- Start Page
- 313
- End Page
- 316
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/14901
- DOI
- 10.1016/j.jocn.2012.02.029
- ISSN
- 0967-5868
1532-2653
- Abstract
- Corticobasal degeneration (CBD) is characterized by various clinical manifestations including corticobasal syndrome, progressive supranuclear palsy-like syndrome and frontotemporal dementia. Focal cortical atrophy syndrome as the initial manifestation rarely occurs in CBD. Here, we present a 62-year-old man and a 70-year-old man who were admitted due to clumsiness in the arms. On initial neurological examination, they showed asymmetric limb apraxia without parkinsonism or global cognitive dysfunction. Brain MRI showed focal atrophy in the frontal and prefrontal cortices, and brain positron emission tomography scan revealed decreased metabolism in these same brain locations. Although these patients developed parkinsonism and dystonia within several years, the neurological signs were limited to the arms for a long period. "Progressive upper-body apraxia" may be a rare clinical manifestation of CBD which shows a benign clinical outcome. The patients described may enhance our understanding of the clinical heterogeneity of this disease. (C) 2012 Elsevier Ltd. All rights reserved.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > College of Medicine > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/14901)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.