Is There a Role for Adjuvant Therapy in RO Resected Gallbladder Cancer?: A Propensity Score-Matched Analysis
DC Field | Value | Language |
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dc.contributor.author | Go, Se-Il | - |
dc.contributor.author | Kim, Young Saing | - |
dc.contributor.author | Hwang, In Gyu | - |
dc.contributor.author | Kim, Eun Young | - |
dc.contributor.author | Oh, Sung Yong | - |
dc.contributor.author | Ji, Jun Ho | - |
dc.contributor.author | Song, Haa-Na | - |
dc.contributor.author | Park, Se Hoon | - |
dc.contributor.author | Park, Joon Oh | - |
dc.contributor.author | Kang, Jung Hun | - |
dc.date.available | 2019-01-22T14:23:07Z | - |
dc.date.issued | 2016-10 | - |
dc.identifier.issn | 1598-2998 | - |
dc.identifier.issn | 2005-9256 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/1728 | - |
dc.description.abstract | Purpose The purpose of this study is to assess the role of adjuvant therapy in stage I-Ill gallbladder cancer (GBC) patients who have undergone RO resection. Materials and Methods Clinical data were collected on 441 consecutive patients who underwent RO resection for stage I-Ill GBC. Eligible patients were classified into adjuvant therapy and surveillance only groups. Propensity score matching (PSM) between the two groups was performed, adjusting clinical factors. Results In total, 84 and 279 patients treated with adjuvant therapy and followed up with surveillance only, respectively, were included in the analysis. Before PSM, the 5-year relapse-free survival (RFS) rate was lower in the adjuvant therapy group than in the surveillance only group (50.8% vs. 74.8%, p < 0.001), although there was no statistically significant difference in the 5-year overall survival (OS) rate (66.2% vs. 79.5%, p=0.089). After the PSM, baseline characteristics became comparable and there were no differences in the 5-year RFS (50.8% vs. 64.8%, p=0.319) and OS (66.2% vs. 70.4%, p=0.703) rates between the two groups. Conclusion The results suggest that fluoropyrimidine-based adjuvant therapy is not indicated in stage I-Ill GBC patients who have undergone RO resection. | - |
dc.format.extent | 12 | - |
dc.publisher | KOREAN CANCER ASSOCIATION | - |
dc.title | Is There a Role for Adjuvant Therapy in RO Resected Gallbladder Cancer?: A Propensity Score-Matched Analysis | - |
dc.type | Article | - |
dc.identifier.doi | 10.4143/crt.2015.502 | - |
dc.identifier.bibliographicCitation | CANCER RESEARCH AND TREATMENT, v.48, no.4, pp 1274 - 1285 | - |
dc.identifier.kciid | ART002154648 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000385212800012 | - |
dc.identifier.scopusid | 2-s2.0-84996757752 | - |
dc.citation.endPage | 1285 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 1274 | - |
dc.citation.title | CANCER RESEARCH AND TREATMENT | - |
dc.citation.volume | 48 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Gallbladder neoplasms | - |
dc.subject.keywordAuthor | Adjuvant chemotherapy | - |
dc.subject.keywordAuthor | Adjuvant chemoradiotherapy | - |
dc.subject.keywordAuthor | Survival | - |
dc.subject.keywordAuthor | Propensity score | - |
dc.subject.keywordPlus | BILIARY-TRACT CANCER | - |
dc.subject.keywordPlus | SURGICAL RESECTION | - |
dc.subject.keywordPlus | PROGNOSTIC-FACTORS | - |
dc.subject.keywordPlus | GEMCITABINE | - |
dc.subject.keywordPlus | CHEMOTHERAPY | - |
dc.subject.keywordPlus | SURVIVAL | - |
dc.subject.keywordPlus | CHOLANGIOCARCINOMA | - |
dc.subject.keywordPlus | RADIOTHERAPY | - |
dc.subject.keywordPlus | STATISTICS | - |
dc.subject.keywordPlus | CARCINOMA | - |
dc.relation.journalResearchArea | Oncology | - |
dc.relation.journalWebOfScienceCategory | Oncology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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