Temperature-Responsive Hydrogel-Coated Gold Nanoshells
DC Field | Value | Language |
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dc.contributor.author | Park, Hye Hun | - |
dc.contributor.author | Srisombat, La-ongnuan | - |
dc.contributor.author | Jamison, Andrew C. | - |
dc.contributor.author | Liu, Tingting | - |
dc.contributor.author | Marquez, Maria D. | - |
dc.contributor.author | Park, Hansoo | - |
dc.contributor.author | Lee, Sungbae | - |
dc.contributor.author | Lee, Tai-Chou | - |
dc.contributor.author | Lee, T. Randall | - |
dc.date.available | 2019-05-28T03:39:21Z | - |
dc.date.issued | 2018-06 | - |
dc.identifier.issn | 2310-2861 | - |
dc.identifier.issn | 2310-2861 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/18703 | - |
dc.description.abstract | Gold nanoshells (similar to 160 nm in diameter) were encapsulated within a shell of temperature-responsive poly(N-isopropylacrylamide-co-acrylic acid) (P(NIPAM-co-AA)) using a surface-bound rationally-designed free radical initiator in water for the development of a photothermally-induced drug-delivery system. The morphologies of the resultant hydrogel-coated nanoshells were analyzed by scanning electron microscopy (SEM), while the temperature-responsive behavior of the nanoparticles was characterized by dynamic light scattering (DLS). The diameter of the P(NIPAM-co-AA) encapsulated nanoshells decreased as the solution temperature was increased, indicating a collapse of the hydrogel layer with increasing temperatures. In addition, the optical properties of the composite nanoshells were studied by UV-visible spectroscopy. The surface plasmon resonance (SPR) peak of the hydrogel-coated nanoshells appeared at similar to 800 nm, which lies within the tissue-transparent range that is important for biomedical applications. Furthermore, the periphery of the particles was conjugated with the model protein avidin to modify the hydrogel-coated nanoshells with a fluorescent-tagged biotin, biotin-4-fluorescein (biotin-4-FITC), for colorimetric imaging/monitoring. | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | MDPI AG | - |
dc.title | Temperature-Responsive Hydrogel-Coated Gold Nanoshells | - |
dc.type | Article | - |
dc.identifier.doi | 10.3390/gels4020028 | - |
dc.identifier.bibliographicCitation | Gels, v.4, no.2 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000461124800004 | - |
dc.identifier.scopusid | 2-s2.0-85056606353 | - |
dc.citation.number | 2 | - |
dc.citation.title | Gels | - |
dc.citation.volume | 4 | - |
dc.type.docType | Article | - |
dc.publisher.location | 스위스 | - |
dc.subject.keywordAuthor | drug delivery | - |
dc.subject.keywordAuthor | temperature responsive | - |
dc.subject.keywordAuthor | gold nanoshell | - |
dc.subject.keywordAuthor | hydrogel coating | - |
dc.subject.keywordPlus | SELF-ASSEMBLED MONOLAYERS | - |
dc.subject.keywordPlus | OPTICAL-PROPERTIES | - |
dc.subject.keywordPlus | POLY(N-ISOPROPYLACRYLAMIDE) NANOCAPSULES | - |
dc.subject.keywordPlus | N-ISOPROPYLACRYLAMIDE | - |
dc.subject.keywordPlus | NANOPARTICLE SENSOR | - |
dc.subject.keywordPlus | COPOLYMER MICROGELS | - |
dc.subject.keywordPlus | SILVER NANOSHELLS | - |
dc.subject.keywordPlus | PHASE-TRANSITION | - |
dc.subject.keywordPlus | DRUG-DELIVERY | - |
dc.subject.keywordPlus | AU | - |
dc.relation.journalResearchArea | Polymer Science | - |
dc.relation.journalWebOfScienceCategory | Polymer Science | - |
dc.description.journalRegisteredClass | esci | - |
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