Analysis of oropharyngeal microbiota between the patients with bronchial asthma and the non-asthmatic persons
DC Field | Value | Language |
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dc.contributor.author | Dang, H.T. | - |
dc.contributor.author | Kim, S.A. | - |
dc.contributor.author | Park, H.K. | - |
dc.contributor.author | Shin, Jong Wook | - |
dc.contributor.author | Park, Sang-Gue | - |
dc.contributor.author | Kim, Wonyong | - |
dc.date.available | 2019-05-29T03:36:44Z | - |
dc.date.issued | 2013-12 | - |
dc.identifier.issn | 1598-2467 | - |
dc.identifier.issn | 2093-0429 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/19822 | - |
dc.description.abstract | Bronchial asthma can be triggered by microbial agents in the oropharynx. This study was designed to identify the differences in microbiota of oropharynx of bronchial asthmatic patients in contrast to normal controls. In order to resolve the qualitative and quantitative diversity of the 16S rRNA gene present in the oropharynx microbiota of 4 patients and 4 controls, we compared microbial communities using Sanger sequencing and 376 sequences of 16S rRNA gene were analyzed. Of the total microbial diversity detected in the oropharynx in asthmatic patients 45.6% comprised members of the Firmicutes. In contrast, Proteobacteria (44.0%) dominated the oropharyngeal microbiota in the normal control group. Members of the Bacteroidetes, Fusobacteria, Actinobacteria, TM7, Cyanobacteria and unclassified bacteria were present in both groups. In conclusion, the difference in the microbiota of the oropharynx between patients and normal individuals could trigger symptomatic attacks in bronchial asthma. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | The Korean Society for Mocrobiology / The Korean Society of Virology | - |
dc.title | Analysis of oropharyngeal microbiota between the patients with bronchial asthma and the non-asthmatic persons | - |
dc.type | Article | - |
dc.identifier.doi | 10.4167/jbv.2013.43.4.270 | - |
dc.identifier.bibliographicCitation | Journal of Bacteriology and Virology, v.43, no.4, pp 270 - 278 | - |
dc.identifier.kciid | ART001836542 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-84908040326 | - |
dc.citation.endPage | 278 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 270 | - |
dc.citation.title | Journal of Bacteriology and Virology | - |
dc.citation.volume | 43 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Bronchial asthma | - |
dc.subject.keywordAuthor | Metagenome | - |
dc.subject.keywordAuthor | Microbiota | - |
dc.subject.keywordPlus | RNA 16S | - |
dc.subject.keywordPlus | Actinobacteria | - |
dc.subject.keywordPlus | article | - |
dc.subject.keywordPlus | asthma | - |
dc.subject.keywordPlus | bacterial genome | - |
dc.subject.keywordPlus | bacterium identification | - |
dc.subject.keywordPlus | Bacteroides | - |
dc.subject.keywordPlus | case report | - |
dc.subject.keywordPlus | controlled study | - |
dc.subject.keywordPlus | cyanobacterium | - |
dc.subject.keywordPlus | disease association | - |
dc.subject.keywordPlus | DNA sequence | - |
dc.subject.keywordPlus | female | - |
dc.subject.keywordPlus | Firmicutes | - |
dc.subject.keywordPlus | Fusobacterium | - |
dc.subject.keywordPlus | genetic conservation | - |
dc.subject.keywordPlus | genetic variability | - |
dc.subject.keywordPlus | human | - |
dc.subject.keywordPlus | Leptotrichia | - |
dc.subject.keywordPlus | male | - |
dc.subject.keywordPlus | metagenomics | - |
dc.subject.keywordPlus | microbial community | - |
dc.subject.keywordPlus | microbial diversity | - |
dc.subject.keywordPlus | mouth flora | - |
dc.subject.keywordPlus | Neisseria | - |
dc.subject.keywordPlus | nonhuman | - |
dc.subject.keywordPlus | Prevotella | - |
dc.subject.keywordPlus | Proteobacteria | - |
dc.subject.keywordPlus | qualitative research | - |
dc.subject.keywordPlus | quantitative study | - |
dc.subject.keywordPlus | RNA gene | - |
dc.subject.keywordPlus | Rothia | - |
dc.subject.keywordPlus | sequence homology | - |
dc.subject.keywordPlus | species dominance | - |
dc.subject.keywordPlus | Streptococcus | - |
dc.subject.keywordPlus | Veillonella | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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