Comparative diagnostic accuracy of dual-energy CT myocardial perfusion imaging by monochromatic energy versus material decomposition methods

Abstract

Purpose: To compare the diagnostic value of monochromatic and material decomposition (MD) dual-energy computed tomography (DECT) imaging for the evaluation of ischemia. Methods: Patients with suspected coronary artery disease underwent rest-stress DECT and SPECT perfusion imaging. DECT images were reconstructed between 40 and 140 keV and through MD of iodine/muscle. Results: MD and monochromatic imaging had a sensitivity, specificity, negative predictive, positive predictive value, and accuracy of 89%, 40%, 67%, 73% and 71%; and 91%, 67%, 67%, 91% and 86%, respectively (p = 0.05). Conclusion: DECT using monochromatic energy displayed a non -significantly higher diagnostic accuracy for myocardial ischemia as compared with DECT MD.