Human skin safety test of green tea cell extracts in condition of allergic contact dermatitisHuman Skin Safety Test of Green Tea Cell Extracts in Condition of Allergic Contact Dermatitis
- Authors
- Kim, H.K.; Choi, S.Y.; Chang, H.K.; D Center, Yongin 446-904, South Korea; Baek, S.Y.; D Center, Yongin 446-904, South Korea; Chung, J.O.; D Center, Yongin 446-904, South Korea; Rha, C.S.; D Center, Yongin 446-904, South Korea; Kim, B.J.; Kim, M.N.
- Issue Date
- Jun-2012
- Publisher
- 한국독성학회
- Keywords
- Allergic contact dermatitis; Anti-inflammatory; Green tea; Skin toxicity
- Citation
- Toxicological Research, v.28, no.2, pp 113 - 116
- Pages
- 4
- Journal Title
- Toxicological Research
- Volume
- 28
- Number
- 2
- Start Page
- 113
- End Page
- 116
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/20889
- DOI
- 10.5487/TR.2012.28.2.113
- ISSN
- 1976-8257
2234-2753
- Abstract
- Various kinds of positive effects of green tea extracts had been studied for long time which included antiinflammation, anti-aging, and cardiometabolic effects. Although topical steroid and non-steroidal calcineurin inhibitors may control clinical symptoms of allergic contact dermatitis, some of patients also present allergic reaction to these topical agents. Therefore, we have tried green tea extracts for managing this skin disorder with expectation of anti-inflammatory effect without potential side effects including skin irritation and toxic responses. The toxicity test of green tea extract also did not show any sign of irritation in the skin throughout the test period. Moderate severity of allergic contact dermatitis presented satisfactory clinical outcome at second week follow-up which was final visit of outpatient. This result mean that green tea extract has a positive effect for managing allergic contact dermatitis but its potency and efficacy seem to be so not strong enough to control moderate severity allergy skin lesion. In this pilot study, we were able to conclude that green tea cell extracts might be applied for potential anti-inflammatory soaking without skin toxicity.
- Files in This Item
- There are no files associated with this item.
- Appears in
Collections - College of Medicine > College of Medicine > 1. Journal Articles
![qrcode](https://api.qrserver.com/v1/create-qr-code/?size=55x55&data=https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/20889)
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.