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Discovery of small molecules that enhance astrocyte differentiation in rat fetal neural stem cells
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Chang, Dong Jo | - |
| dc.contributor.author | Jeong, Mi Young | - |
| dc.contributor.author | Song, Jiho | - |
| dc.contributor.author | Jin, Chang Yun | - |
| dc.contributor.author | Suh, Young-Ger | - |
| dc.contributor.author | Kim, Hyun-Jung | - |
| dc.contributor.author | Min, Kyung Hoon | - |
| dc.date.available | 2019-05-29T09:38:32Z | - |
| dc.date.issued | 2011-12 | - |
| dc.identifier.issn | 0960-894X | - |
| dc.identifier.issn | 1464-3405 | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/21044 | - |
| dc.description.abstract | 1,3,4-Oxadiazole derivatives were found to enhance astrocyte differentiation in rat fetal neural stem cells (NSCs). Differentiation activity was assessed by immunocytochemistry and analysis of mRNA expression of astrocyte markers, GFAP and S100. Compounds 7 and 8 showed approximately a two-fold increase in astrocyte differentiation without engagement of neuronal differentiation and detectable cytotoxicity. (C) 2011 Elsevier Ltd. All rights reserved. | - |
| dc.format.extent | 4 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
| dc.title | Discovery of small molecules that enhance astrocyte differentiation in rat fetal neural stem cells | - |
| dc.type | Article | - |
| dc.identifier.doi | 10.1016/j.bmcl.2011.09.099 | - |
| dc.identifier.bibliographicCitation | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.21, no.23, pp 7050 - 7053 | - |
| dc.description.isOpenAccess | N | - |
| dc.identifier.wosid | 000296717600024 | - |
| dc.identifier.scopusid | 2-s2.0-80255126189 | - |
| dc.citation.endPage | 7053 | - |
| dc.citation.number | 23 | - |
| dc.citation.startPage | 7050 | - |
| dc.citation.title | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
| dc.citation.volume | 21 | - |
| dc.type.docType | Article | - |
| dc.publisher.location | 영국 | - |
| dc.subject.keywordAuthor | Neural stem cell | - |
| dc.subject.keywordAuthor | Small molecule | - |
| dc.subject.keywordAuthor | Astrocyte | - |
| dc.subject.keywordAuthor | Differentiation | - |
| dc.subject.keywordAuthor | 1,3,4-Oxadiazole | - |
| dc.subject.keywordPlus | PROGENITOR CELLS | - |
| dc.subject.keywordPlus | NEURONAL DIFFERENTIATION | - |
| dc.subject.keywordPlus | NEUROGENESIS | - |
| dc.subject.keywordPlus | MAINTENANCE | - |
| dc.subject.keywordPlus | DISEASE | - |
| dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
| dc.relation.journalResearchArea | Chemistry | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
| dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
| dc.description.journalRegisteredClass | sci | - |
| dc.description.journalRegisteredClass | scie | - |
| dc.description.journalRegisteredClass | scopus | - |
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