Preparation of a visible light-reactive low molecular-O-carboxymethyl chitosan (LM-O-CMCS) derivative and applicability as an anti-adhesion agent

Abstract

Photo-reactive low molecular-O-carboxymethyl chitosan (LM-O-CMCS) was synthesized by introducing a furfuryl group to the amine groups of LM-O-CMCS. The prepared photo-reactive LM-O-CMCS was characterized by FTIR, (1)H NMR, and a cross-linking test, whereas scanning Auger electron microscopy (SAM) and a MTT assay were used to confirm the cell viability. The water contact angle measurement and cell attachment test were carried out to determine the applicability of LM-O-CMCS as an anti-adhesion agent.