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Complete genomic characterization of cell culture adapted human G12P[6] rotaviruses isolated from South Korea
- Authors
- Van Thai Than; Van Phan Le; Lim, Inseok; Kim, Wonyong
- Issue Date
- Jun-2011
- Publisher
- SPRINGER
- Keywords
- G12; Korean rotavirus; Phylogenetic analysis
- Citation
- VIRUS GENES, v.42, no.3, pp 317 - 322
- Pages
- 6
- Journal Title
- VIRUS GENES
- Volume
- 42
- Number
- 3
- Start Page
- 317
- End Page
- 322
- ISSN
- 0920-8569
1572-994X
- Abstract
- Two unusual human rotavirus G12 strains, CAU195 and CAU214, were isolated from female pediatric diarrhea patients under 12 months of age in 2006 using a cell culture system and their full genome sequences were analyzed. The 11 gene segments of both Korean G12 strains were classified as G12-P[6]-R1-C1-M1-I1-A1-N1-T1-E1-H1 genotypes. Notably, the Korean strains were of the same genotypes as previously reported strains isolated from Bangladesh in 2003 (Dhaka12-03), from the United States in 2005-2006 (US6597), and from Germany in 2008 (GER126-08 and GER172-08), suggesting that closely related G12P[6] strains are persistent and widespread.
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