Identification of Proteins Differentially Expressed in Gastric Cancer Cells with High Metastatic Potential for Invasion to Lymph Nodes
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Lee, Do Hee | - |
dc.contributor.author | Lee, Youra | - |
dc.contributor.author | Ryu, Joohyun | - |
dc.contributor.author | Park, Sung Goo | - |
dc.contributor.author | Cho, Sayeon | - |
dc.contributor.author | Lee, Je-Jung | - |
dc.contributor.author | Choi, Chan | - |
dc.contributor.author | Park, Byoung Chul | - |
dc.date.available | 2019-05-29T13:34:05Z | - |
dc.date.issued | 2011-06 | - |
dc.identifier.issn | 1016-8478 | - |
dc.identifier.issn | 0219-1032 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/21522 | - |
dc.description.abstract | In a search for proteins involved in cancer metastasis, we analyzed proteomes of the human gastric cancer cell OCUM-2M and its metastatic subline OCUM-2MLN. We observed that aspartate aminotransferase (AAT), D-site binding protein (DBP), and anterior gradient protein 2 (AGR2) are differentially expressed in metastatic OCUM-2MLN cells. Measurement of protein expression in clinical samples indicated that DBP and AAT are also down-regulated in metastatic adenocarcinoma. Additionally, urokinase-type tissue plasminogen activator is up-regulated in OCUM-2MLN cells and also in metastatic gastric cancer samples. Collectively, these results raise a possibility that AAT, DBP and AGR2 are functionally implicated in the invasiveness of gastric cancer cells. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | KOREAN SOC MOLECULAR & CELLULAR BIOLOGY | - |
dc.title | Identification of Proteins Differentially Expressed in Gastric Cancer Cells with High Metastatic Potential for Invasion to Lymph Nodes | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s10059-011-1053-z | - |
dc.identifier.bibliographicCitation | MOLECULES AND CELLS, v.31, no.6, pp 563 - 571 | - |
dc.identifier.kciid | ART001557927 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000292965400010 | - |
dc.identifier.scopusid | 2-s2.0-79960606016 | - |
dc.citation.endPage | 571 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 563 | - |
dc.citation.title | MOLECULES AND CELLS | - |
dc.citation.volume | 31 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | AAT | - |
dc.subject.keywordAuthor | AGR2 | - |
dc.subject.keywordAuthor | DBP | - |
dc.subject.keywordAuthor | gastric cancer | - |
dc.subject.keywordAuthor | metastasis | - |
dc.subject.keywordAuthor | proteome | - |
dc.subject.keywordPlus | 2-DIMENSIONAL GEL-ELECTROPHORESIS | - |
dc.subject.keywordPlus | PLASMINOGEN-ACTIVATOR EXPRESSION | - |
dc.subject.keywordPlus | MASS-SPECTROMETRY | - |
dc.subject.keywordPlus | BREAST-CANCER | - |
dc.subject.keywordPlus | ESTROGEN-RECEPTOR | - |
dc.subject.keywordPlus | TUMOR PROGRESSION | - |
dc.subject.keywordPlus | HUMAN HOMOLOG | - |
dc.subject.keywordPlus | GENE XAG-2 | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.subject.keywordPlus | GROWTH | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Cell Biology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.