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Conduction aphasia as an initial symptom in a patient with Creutzfeldt-Jakob disease
- Authors
- Song, Ji-Eun; Yang, Dong-Won; Seo, Hyun-Jin; Ha, Sam-Yeol; Park, Kwang-Yeol; Kwon, Oh-Sang; Youn, Young Chul
- Issue Date
- Oct-2010
- Publisher
- ELSEVIER SCI LTD
- Keywords
- Brain images; Conduction aphasia; Sporadic Creutzfeldt-Jakob disease
- Citation
- JOURNAL OF CLINICAL NEUROSCIENCE, v.17, no.10, pp 1341 - 1343
- Pages
- 3
- Journal Title
- JOURNAL OF CLINICAL NEUROSCIENCE
- Volume
- 17
- Number
- 10
- Start Page
- 1341
- End Page
- 1343
- ISSN
- 0967-5868
1532-2653
- Abstract
- We report a 59-year-old woman who presented to our facility with conduction aphasia as an initial symptom which, within 3 months, was followed by generalized myoclonus and global aphasia. She had difficulty repeating words during the Korean-Western Aphasia Battery test. Diffusion-weighted MRI demonstrated ribbon-like hyperintensities in the bilateral temporal, parietal and occipital cerebral cortex. An electroencephalogram showed periodic discharges over the bilateral hemispheres, while single photo emission CT revealed diminished perfusion. After a positive finding of the 14-3-3 protein in her cerebrospinal fluid, she was diagnosed as having probable sporadic Creutzfeldt-Jakob disease. (C) 2010 Elsevier Ltd. All rights reserved.
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