Proteomic Analysis of Bronchoalveolar Lavage Fluid Obtained from Rats Exposed to Formaldehyde
DC Field | Value | Language |
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dc.contributor.author | Ahn, Kyong Hoon | - |
dc.contributor.author | Kim, Seok Kyun | - |
dc.contributor.author | Lee, Jung Min | - |
dc.contributor.author | Jeon, Hyung Jun | - |
dc.contributor.author | Lee, Dong Hoon | - |
dc.contributor.author | Kim, Dae Kyong | - |
dc.date.available | 2019-05-30T01:34:56Z | - |
dc.date.issued | 2010-06 | - |
dc.identifier.issn | 1344-9702 | - |
dc.identifier.issn | 1347-5207 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/22420 | - |
dc.description.abstract | Formaldehyde is an industrial chemical used in the manufacture of building materials and household products, and is one of the major pollutants that cause "sick building syndrome." Formaldehyde causes a wide range of toxic effects such as the formation of DNA-protein cross-links, activation of the immune system, and sensory irritation. In the present study, we investigated the effects of formaldehyde inhalation on protein levels in rat bronchoalveolar lavage fluid with a proteomics approach. Using two-dimensional gel electrophoresis and matrix-assisted laser desorption/ionization-time-of-flight mass spectroscopy, we identified aldo-keto reductase IB10 as a possible biomarker for formaldehyde inhalation. This study may contribute to a better understanding of the mechanisms involved in the pathogenesis of formaldehyde exposure. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | PHARMACEUTICAL SOC JAPAN | - |
dc.title | Proteomic Analysis of Bronchoalveolar Lavage Fluid Obtained from Rats Exposed to Formaldehyde | - |
dc.type | Article | - |
dc.identifier.doi | 10.1248/jhs.56.287 | - |
dc.identifier.bibliographicCitation | JOURNAL OF HEALTH SCIENCE, v.56, no.3, pp 287 - 295 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000278115000007 | - |
dc.identifier.scopusid | 2-s2.0-77953305792 | - |
dc.citation.endPage | 295 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 287 | - |
dc.citation.title | JOURNAL OF HEALTH SCIENCE | - |
dc.citation.volume | 56 | - |
dc.type.docType | Article | - |
dc.publisher.location | 일본 | - |
dc.subject.keywordAuthor | formaldehyde | - |
dc.subject.keywordAuthor | bronchoalveolar lavage fluid | - |
dc.subject.keywordAuthor | two-dimensional gel electrophoresis | - |
dc.subject.keywordAuthor | aldo-keto reductase | - |
dc.subject.keywordPlus | KETO REDUCTASE FAMILY | - |
dc.subject.keywordPlus | INCREASE LIPOCORTIN-I | - |
dc.subject.keywordPlus | INHALED FORMALDEHYDE | - |
dc.subject.keywordPlus | RESPIRATORY-TRACT | - |
dc.subject.keywordPlus | PLASMA-PROTEINS | - |
dc.subject.keywordPlus | LUNG-DISEASE | - |
dc.subject.keywordPlus | IDENTIFICATION | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | GENE | - |
dc.subject.keywordPlus | EPITHELIUM | - |
dc.relation.journalResearchArea | Toxicology | - |
dc.relation.journalWebOfScienceCategory | Toxicology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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