Clinical Spectrum of Reflux Esophagitis Among 25,536 Koreans Who Underwent a Health Check-up A Nationwide Multicenter Prospective, Endoscopy-based Study
- Authors
- Shim, Ki-Nam; Hong, Su Jin; Sung, Jae Kyu; Park, Kyung Sik; Kim, Seong-Eun; Park, Hyun-Shin; Kim, Young Sun; Lim, Seon Hee; Kim, Chung Hyeon; Park, Min Jung; Kim, Jeong Yoon; Cho, Kyung Ran; Kim, Donghee; Park, Seun Ja; Jee, Sam-Ryong; Kim, Jin Il; Park, Joon Yong; Song, Geun Am; Jung, Hwoon-Yong; Lee, Yong Chan; Kim, Jae Gyu; Kim, Jae J.; Kim, Nayoung; Park, Soo-Heon; Jung, Hyun Chae; Chung, In-Sik
- Issue Date
- Aug-2009
- Publisher
- LIPPINCOTT WILLIAMS & WILKINS
- Keywords
- reflux esophagitis; endoscopy; reflux symptom
- Citation
- JOURNAL OF CLINICAL GASTROENTEROLOGY, v.43, no.7, pp 632 - 638
- Pages
- 7
- Journal Title
- JOURNAL OF CLINICAL GASTROENTEROLOGY
- Volume
- 43
- Number
- 7
- Start Page
- 632
- End Page
- 638
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/23063
- DOI
- 10.1097/MCG.0b013e3181855055
- ISSN
- 0192-0790
1539-2031
- Abstract
- Background: Gastroesophageal reflux is a commonly encountered condition, but detailed data on reflux symptoms in Asian countries are lacking. Goals: To evaluate the prevalence and to document the clinical spectrum of endoscopic reflux esophagitis (RE). Study: A total 25,536 subjects underwent an upper gastrointestinal endoscopic examination as part of a health check, and completed a gastroesophageal reflux questionnaire. Endoscopic findings classified according to the Los Angeles (LA) classification and the data from gastroesophageal reflux questionnaire were analyzed. Results: On the basis of endoscopic findings, 2019 subjects (7.91%) were found to have RE: 5.87% in LA-A; 1.84% in LA-B; 0.18% in LA-C; and 0.02% in LA-D. Heartburn. acid regurgitation, chest pain, hoarseness, globus sensation. Cough, and epigastric soreness were found to be associated with RE (P < 0.05). Heartburn. acid regurgitation, and epigastric soreness were more frequent in LA-B than in LA-A (P < 0.05). Epigastric soreness was most bothersome in LA-A and LA-B, and acid regurgitation was most bothersome in LA-C and LA-D (P<0.01). Heartburn. hoarseness, and globus sensation were more frequent in men with RE, and acid regurgitation was most common in women. Conclusions: The prevalence of RE was found to be 7.91% in Korea, and the Profiles of reflux symptoms were found to depend on grade of RE and sex.
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