Water Chestnut (Trapa japonica Flerov.) Exerts Inhibitory Effect on Postprandial Glycemic Response in Rats and Free Radical Scavenging Activity in vitro
DC Field | Value | Language |
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dc.contributor.author | Kang, Ming-Jung | - |
dc.contributor.author | Lee, Soo-Kyung | - |
dc.contributor.author | Song, Ji-Hyun | - |
dc.contributor.author | Kim, Mi-Eun | - |
dc.contributor.author | Kim, Myo-Jeong | - |
dc.contributor.author | Jang, Joung-Soon | - |
dc.contributor.author | Lee, Jai-Hyun | - |
dc.contributor.author | Kim, Jung-In | - |
dc.date.available | 2019-05-30T03:32:49Z | - |
dc.date.issued | 2009-06 | - |
dc.identifier.issn | 1226-7708 | - |
dc.identifier.issn | 2092-6456 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/23164 | - |
dc.description.abstract | The alpha-glucosidase inhibitory and antioxidant effects of water chestnut (Trapa japonica Flerov.) were assessed to explore its possible use as an anti-diabetic agent. Methanol extracts of the fruit shell and meat of water chestnut were assayed for inhibitory activity against yeast a-glucosidase and 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical. scavenging activity. Effect of fruit shell extract on postprandial glucose response was assessed. Compared with fruit meat, shell extract showed stronger inhibition against alpha-glucosidase with an IC50 of 273 mu g/mL. Oral administration of fruit shell extract (500 mg/kg) significantly lowered the postprandial area under the glucose response curve to starch (1 g/kg) in streptozotocin (STZ)-induced diabetic rats (p<0.01). Compared with fruit meat, shell extract showed stronger scavenging activity against DPPH, with an IC50 of 27.1 mu g/mL. The results indicate that the fruit shell of water chestnut was effective in controlling postprandial hyperglycemia and exerted an antioxidant effect. Therefore, water chestnut may be useful in treating diabetes. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | KOREAN SOCIETY FOOD SCIENCE & TECHNOLOGY-KOSFOST | - |
dc.title | Water Chestnut (Trapa japonica Flerov.) Exerts Inhibitory Effect on Postprandial Glycemic Response in Rats and Free Radical Scavenging Activity in vitro | - |
dc.type | Article | - |
dc.identifier.bibliographicCitation | FOOD SCIENCE AND BIOTECHNOLOGY, v.18, no.3, pp 808 - 812 | - |
dc.identifier.kciid | ART001354625 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000267693600038 | - |
dc.citation.endPage | 812 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 808 | - |
dc.citation.title | FOOD SCIENCE AND BIOTECHNOLOGY | - |
dc.citation.volume | 18 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | alpha-glucosidase | - |
dc.subject.keywordAuthor | antioxidant effect | - |
dc.subject.keywordAuthor | postprandial hyperglycemia | - |
dc.subject.keywordAuthor | Trapa japonica Flerov. | - |
dc.subject.keywordPlus | DEPENDENT DIABETES-MELLITUS | - |
dc.subject.keywordPlus | ALPHA-GLUCOSIDASE INHIBITORS | - |
dc.subject.keywordPlus | OXIDATIVE STRESS | - |
dc.subject.keywordPlus | EUCOMMIA-ULMOIDES | - |
dc.subject.keywordPlus | SAURURUS-CHINENSIS | - |
dc.subject.keywordPlus | FASTING GLUCOSE | - |
dc.subject.keywordPlus | ANIMAL-MODELS | - |
dc.subject.keywordPlus | EXTRACT | - |
dc.subject.keywordPlus | HYPERGLYCEMIA | - |
dc.subject.keywordPlus | ACARBOSE | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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