Absolute Configurations of (+/-)-Glabridin Enantiomers
DC Field | Value | Language |
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dc.contributor.author | Kim, Mihyang | - |
dc.contributor.author | Kim, Soo-Un | - |
dc.contributor.author | Kim, Yong-ung | - |
dc.contributor.author | Han, Jaehong | - |
dc.date.available | 2019-05-30T03:37:53Z | - |
dc.date.issued | 2009-02 | - |
dc.identifier.issn | 1229-5949 | - |
dc.identifier.issn | 1229-5949 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/23313 | - |
dc.description.abstract | Concerned with ambiguous stereochemistry assignment of natural (+)-glabridin, absolute configurations of (+/-)-glabridin enantiomers were studied with synthetic glabridin. Synthetic glabridin enantiomers were separated by semi-preparative Sumi-chiral column chromatography, and characterized by UV-Vis and NMR spectroscopy. Three-dimensional molecular structure of glabridin was obtained as equatorial Ph-3 half chair chroman ring from semi-empirical PM3 calculation, and refined by coupling constants in H-1 NMR spectrum. Finally, absolute configurations of two enantiomers were determined by circular dichroism spectroscopy based on the empirical helicity rules. Absolute configuration of natural (+)-glabridin was confirmed as (R)-glabridin, as known. | - |
dc.format.extent | 4 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | WILEY-V C H VERLAG GMBH | - |
dc.title | Absolute Configurations of (+/-)-Glabridin Enantiomers | - |
dc.type | Article | - |
dc.identifier.doi | 10.5012/bkcs.2009.30.2.415 | - |
dc.identifier.bibliographicCitation | BULLETIN OF THE KOREAN CHEMICAL SOCIETY, v.30, no.2, pp 415 - 418 | - |
dc.identifier.kciid | ART001524406 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000264903700029 | - |
dc.identifier.scopusid | 2-s2.0-71749111413 | - |
dc.citation.endPage | 418 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 415 | - |
dc.citation.title | BULLETIN OF THE KOREAN CHEMICAL SOCIETY | - |
dc.citation.volume | 30 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Absolute configuration | - |
dc.subject.keywordAuthor | Circular dichroism (CD) | - |
dc.subject.keywordAuthor | Flavonoids | - |
dc.subject.keywordAuthor | Glabridin | - |
dc.subject.keywordAuthor | Isoflavan | - |
dc.subject.keywordPlus | GLYCYRRHIZA-GLABRA LICORICE | - |
dc.subject.keywordPlus | LOW-DENSITY-LIPOPROTEIN | - |
dc.subject.keywordPlus | IN-VITRO | - |
dc.subject.keywordPlus | BIOLOGICAL-ACTIVITY | - |
dc.subject.keywordPlus | CIRCULAR-DICHROISM | - |
dc.subject.keywordPlus | ISOFLAVAN | - |
dc.subject.keywordPlus | ROOT | - |
dc.subject.keywordPlus | FLAVONOIDS | - |
dc.subject.keywordPlus | CELLS | - |
dc.subject.keywordPlus | EQUOL | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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