The tobacco gene Ntcyc07 confers arsenite tolerance in Saccharomyces cerevisiae by reducing the steady state levels of intracellular arsenic
DC Field | Value | Language |
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dc.contributor.author | Mok, Young Geun | - |
dc.contributor.author | Lee, Byoung Doo | - |
dc.contributor.author | Kim, Young Jin | - |
dc.contributor.author | Lee, Chang Eun | - |
dc.contributor.author | Kim, Dong Gwan | - |
dc.contributor.author | Lee, Joohyun | - |
dc.contributor.author | Shim, Jaekyung | - |
dc.contributor.author | Meng, Yuling | - |
dc.contributor.author | Rosen, Barry P. | - |
dc.contributor.author | Choi, Jong Soon | - |
dc.contributor.author | Shin, Hyoung Sun | - |
dc.contributor.author | Kim, Seong-Ki | - |
dc.contributor.author | Lee, June Seung | - |
dc.contributor.author | Hwang, Seongbin | - |
dc.date.available | 2019-05-30T05:34:37Z | - |
dc.date.issued | 2008-03 | - |
dc.identifier.issn | 0014-5793 | - |
dc.identifier.issn | 1873-3468 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/23809 | - |
dc.description.abstract | We cloned a plant gene, Ntcyc07, conferring arsenite tolerance by expressing a tobacco expression library in WT yeast (Y800). Expression of Ntcyc07 increased the tolerance to As(III) and decreased its accumulation, suggesting that the enhanced As(III) tolerance resulted from a reduction of the intracellular arsenic level. Interestingly, expression of Ntcyc07 increased the expression of the As(III) export carrier ACR3, but repressed that of As(III) uptake channel FPS1. Ntcyc07p interacted with Acr1p, which is the transcriptional activator of ACR3, but not with the ACR3 promoter. Taken together, the data indicated that Ntcyc07p promoted As(HI) tolerance by decreasing the intracellular level of As(III) via increasing the expression of ACR3 and reducing that of FPS1. (C) 2008 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | ELSEVIER SCIENCE BV | - |
dc.title | The tobacco gene Ntcyc07 confers arsenite tolerance in Saccharomyces cerevisiae by reducing the steady state levels of intracellular arsenic | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.febslet.2008.02.030 | - |
dc.identifier.bibliographicCitation | FEBS LETTERS, v.582, no.6, pp 916 - 924 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000257331400015 | - |
dc.identifier.scopusid | 2-s2.0-40149108725 | - |
dc.citation.endPage | 924 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 916 | - |
dc.citation.title | FEBS LETTERS | - |
dc.citation.volume | 582 | - |
dc.type.docType | Article | - |
dc.publisher.location | 네델란드 | - |
dc.subject.keywordAuthor | arsenite | - |
dc.subject.keywordAuthor | cyc07 | - |
dc.subject.keywordAuthor | ACR1 | - |
dc.subject.keywordAuthor | ACR3 | - |
dc.subject.keywordAuthor | FPS1 | - |
dc.subject.keywordAuthor | N. tabaccum | - |
dc.subject.keywordAuthor | S. cerevisiae | - |
dc.subject.keywordPlus | PHASE-SPECIFIC GENE | - |
dc.subject.keywordPlus | CATHARANTHUS-ROSEUS CELLS | - |
dc.subject.keywordPlus | PHOSPHATE-UPTAKE | - |
dc.subject.keywordPlus | HOLCUS-LANATUS | - |
dc.subject.keywordPlus | ARABIDOPSIS | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.subject.keywordPlus | PHYTOCHELATINS | - |
dc.subject.keywordPlus | ACCUMULATION | - |
dc.subject.keywordPlus | REDUCTASE | - |
dc.subject.keywordPlus | MUTANT | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Biophysics | - |
dc.relation.journalResearchArea | Cell Biology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biophysics | - |
dc.relation.journalWebOfScienceCategory | Cell Biology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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