A novel lectin isolated from the hemolymph of the marine hair crab Erimacrus isenbeckii
DC Field | Value | Language |
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dc.contributor.author | Na, Young Jun | - |
dc.contributor.author | Kim, Yu Jeong | - |
dc.contributor.author | Park, Byung Tae | - |
dc.contributor.author | Jung, Byung Wook | - |
dc.contributor.author | Hwang, Kwang Woo | - |
dc.contributor.author | Kim, HaHyung | - |
dc.date.available | 2019-05-30T06:37:23Z | - |
dc.date.issued | 2007-08 | - |
dc.identifier.issn | 0929-8665 | - |
dc.identifier.issn | 1875-5305 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/24204 | - |
dc.description.abstract | A lectin that induces hemagglutination activity in mouse and rabbit erythrocytes has been purified from the hemolymph of the marine hair crab Erimacrus isenbeckii. The results of SDS-PAGE, gel-filtration, affinity and anion-exchange chromatography indicate that this lectin, designated EIL (E. isenbeckii lectin), was successfully purified as a single protein, and comprises a mixture of a major (90%) dimeric and a minor (10%) oligomeric protein with a molecular mass of 116 kDa, with covalent linking between two subunits of 62 and 54 kDa. The activity was maximal at pH 5.6-8.0 and at temperatures below 50 degrees C. The N-terminal amino acid sequences were determined, and these differed greatly from those of other reported lectins from invertebrates, vertebrates, or plants. EIL binds with high specificities to both the O-acetylsialic acid and mannose that are present in bacterial pathogens, which suggests that EIL can act as a defense protein against infection in this crab. | - |
dc.format.extent | 4 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | BENTHAM SCIENCE PUBL LTD | - |
dc.title | A novel lectin isolated from the hemolymph of the marine hair crab Erimacrus isenbeckii | - |
dc.type | Article | - |
dc.identifier.doi | 10.2174/092986607781483714 | - |
dc.identifier.bibliographicCitation | PROTEIN AND PEPTIDE LETTERS, v.14, no.8, pp 800 - 803 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000250570300011 | - |
dc.identifier.scopusid | 2-s2.0-34548689371 | - |
dc.citation.endPage | 803 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 800 | - |
dc.citation.title | PROTEIN AND PEPTIDE LETTERS | - |
dc.citation.volume | 14 | - |
dc.type.docType | Article | - |
dc.publisher.location | 아랍에미리트 | - |
dc.subject.keywordAuthor | erimacrus isenbeckii | - |
dc.subject.keywordAuthor | crab | - |
dc.subject.keywordAuthor | hemolymph | - |
dc.subject.keywordAuthor | lectin | - |
dc.subject.keywordAuthor | O-acetylsialic acid | - |
dc.subject.keywordAuthor | mannose | - |
dc.subject.keywordPlus | ACID-SPECIFIC LECTIN | - |
dc.subject.keywordPlus | NON-SELF-RECOGNITION | - |
dc.subject.keywordPlus | BINDING LECTIN | - |
dc.subject.keywordPlus | PURIFICATION | - |
dc.subject.keywordPlus | MECHANISMS | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalWebOfScienceCategory | Biochemistry & Molecular Biology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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