Combined effects of bovine colostrum and glutamine in diclofenac-induced bacterial translocation in rat
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kim, JW | - |
dc.contributor.author | Jeon, WK | - |
dc.contributor.author | Kim, EJ | - |
dc.date.available | 2019-05-30T07:36:22Z | - |
dc.date.issued | 2005-10 | - |
dc.identifier.issn | 0261-5614 | - |
dc.identifier.issn | 1532-1983 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/24515 | - |
dc.description.abstract | Background & Aims: The aim of this study was to examine whether the combined administration of bovine colostrum and glutamine was able to prevent the nonsteroidal anti-inflammatory drug (NSAID)-induced gut damage and bacterial. translocation (BT) in the rats. Methods: The animal model population of the study consisted of six groups; control group, diclofenac group, diclofenac with milk group, diclofenac with colostrum group, diclofenac with glutamine group and diclofenac with colostrum and glutamine group. The animals with milk, colostrum or glutamine were fed with Low fat milk, liquid colostrum or glutamine by orogastric gavage for 5 days before the dictofenac administration. Intestinal permeability, serum biochemical profiles and intestinal adhesion for assessment of the gut damage, and enteric bacterial. overgrowth and BT at the mesenteric lymph nodes, liver, spleen and systemic blood were measured. Results: Diclofenac caused the increase in gut damage, enteric bacterial. numbers and BT Supplements with colostrum or glutamine reduced these changes induced by diclofenac, but this result was not seen for supplementation with low fat milk. Combined administration of colostrum and glutamine reduced dictofenac-induced gut damage and BT as compared to the use of bovine colostrum alone or glutamine alone. Conclusions: This study suggested that the combined administration of bovine colostrum and glutamine might effectively reduce NSAID-induced gut damage and BT in the rat. (c) 2005 Elsevier Ltd. ALL rights reserved. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | CHURCHILL LIVINGSTONE | - |
dc.title | Combined effects of bovine colostrum and glutamine in diclofenac-induced bacterial translocation in rat | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.clnu.2005.04.004 | - |
dc.identifier.bibliographicCitation | CLINICAL NUTRITION, v.24, no.5, pp 785 - 793 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000232456300010 | - |
dc.identifier.scopusid | 2-s2.0-26044433117 | - |
dc.citation.endPage | 793 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 785 | - |
dc.citation.title | CLINICAL NUTRITION | - |
dc.citation.volume | 24 | - |
dc.type.docType | Article | - |
dc.publisher.location | 스코트랜드 | - |
dc.subject.keywordAuthor | non-steroidal anti-inflammatory agents | - |
dc.subject.keywordAuthor | bacterial translocation | - |
dc.subject.keywordAuthor | bovine colostrum | - |
dc.subject.keywordAuthor | glutamine | - |
dc.subject.keywordPlus | HEALTH FOOD SUPPLEMENT | - |
dc.subject.keywordPlus | GROWTH-FACTOR-I | - |
dc.subject.keywordPlus | HEART-FAILURE | - |
dc.subject.keywordPlus | HORMONE | - |
dc.subject.keywordPlus | PERMEABILITY | - |
dc.subject.keywordPlus | IMMUNONUTRITION | - |
dc.subject.keywordPlus | ENTEROPATHY | - |
dc.subject.keywordPlus | INCREASE | - |
dc.subject.keywordPlus | SEPSIS | - |
dc.subject.keywordPlus | NSAIDS | - |
dc.relation.journalResearchArea | Nutrition & Dietetics | - |
dc.relation.journalWebOfScienceCategory | Nutrition & Dietetics | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.