Hepatoprotective effects of ginseng intestinal metabolite IH-901 on chemical-induced hepatic damage
DC Field | Value | Language |
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dc.contributor.author | Sohn, UD | - |
dc.contributor.author | Ko, SK | - |
dc.contributor.author | Choi, TS | - |
dc.contributor.author | Im, BO | - |
dc.contributor.author | Han, ST | - |
dc.contributor.author | Yang, BW | - |
dc.contributor.author | Sung, JH | - |
dc.contributor.author | Kim, YS | - |
dc.contributor.author | Woo, JG | - |
dc.contributor.author | Cho, YR | - |
dc.contributor.author | Min, YS | - |
dc.contributor.author | Jeong, JH | - |
dc.contributor.author | Lee, BY | - |
dc.date.available | 2019-05-30T07:37:24Z | - |
dc.date.issued | 2005-08 | - |
dc.identifier.issn | 1226-7708 | - |
dc.identifier.issn | 2092-6456 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/24555 | - |
dc.description.abstract | Hepatoprotective effects of white ginseng extract (WGE), and IH-901 (20-O-beta-D-glucopyranosyl-20(S)-protopanaxadiol) derived from intestinal metabolite of ginsenoside Rb, were studied using two experimental animal models with chemical-induced hepatic damage. Administration of WGE (200 and 500 mg/kg) and IH-901 (0.01, 0.05, and 0.1 mM/ kg) significantly decreased aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels in acute hepatitic mice induced by CCl4. Administration of WGE (100 mg/kg) and IH-901 (0.02, 0.04, and 0.08 mM/kg) significantly decreased AST and ALT levels in acute hepatitic rats induced by D-galactosamine. AST and ALT levels of IH-901 groups decreased. These results suggested WGE and IH-901 may have protective effects against chemical-induced hepatic damage. | - |
dc.format.extent | 3 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | KOREAN SOCIETY FOOD SCIENCE & TECHNOLOGY-KOSFOST | - |
dc.title | Hepatoprotective effects of ginseng intestinal metabolite IH-901 on chemical-induced hepatic damage | - |
dc.type | Article | - |
dc.identifier.bibliographicCitation | FOOD SCIENCE AND BIOTECHNOLOGY, v.14, no.4, pp 558 - 560 | - |
dc.identifier.kciid | ART001102978 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000231546400026 | - |
dc.citation.endPage | 560 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 558 | - |
dc.citation.title | FOOD SCIENCE AND BIOTECHNOLOGY | - |
dc.citation.volume | 14 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | hepatoprotective effects | - |
dc.subject.keywordAuthor | white ginseng | - |
dc.subject.keywordAuthor | intestinal metabolite | - |
dc.subject.keywordAuthor | IH-901 | - |
dc.subject.keywordPlus | SAPONINS | - |
dc.relation.journalResearchArea | Food Science & Technology | - |
dc.relation.journalWebOfScienceCategory | Food Science & Technology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | kci | - |
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