Fluorinated quinoid inhibitor: possible 'pure' arylator predicted by the simple theoretical calculation
DC Field | Value | Language |
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dc.contributor.author | Ham, Seung Wook | - |
dc.contributor.author | Choe, Jong-In | - |
dc.contributor.author | Wang, Mei-Fang | - |
dc.contributor.author | Peyregne, Vincent | - |
dc.contributor.author | Carr, Brian I. | - |
dc.date.available | 2019-05-30T08:36:07Z | - |
dc.date.issued | 2004-08 | - |
dc.identifier.issn | 0960-894X | - |
dc.identifier.issn | 1464-3405 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/24790 | - |
dc.description.abstract | We report on the fluorinated form of Cpd 5 as a cell growth inhibitor. This compound is 3-fold more potent than the parent Cpd 5 and is predicted, using the semi-empirical AM1 method to be only an arylator of cysteine-containing proteins, without generating reactive oxygen species. (C) 2004 Elsevier Ltd. All rights reserved. | - |
dc.format.extent | 3 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | PERGAMON-ELSEVIER SCIENCE LTD | - |
dc.title | Fluorinated quinoid inhibitor: possible 'pure' arylator predicted by the simple theoretical calculation | - |
dc.type | Article | - |
dc.identifier.doi | 10.1016/j.bmcl.2004.05.009 | - |
dc.identifier.bibliographicCitation | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, v.14, no.15, pp 4103 - 4105 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000222792800051 | - |
dc.identifier.scopusid | 2-s2.0-3042594182 | - |
dc.citation.endPage | 4105 | - |
dc.citation.number | 15 | - |
dc.citation.startPage | 4103 | - |
dc.citation.title | BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | - |
dc.citation.volume | 14 | - |
dc.type.docType | Article | - |
dc.publisher.location | 영국 | - |
dc.subject.keywordAuthor | Cdc25 inhibitor | - |
dc.subject.keywordAuthor | quinones | - |
dc.subject.keywordAuthor | reduction potential | - |
dc.subject.keywordPlus | DUAL-SPECIFICITY PHOSPHATASES | - |
dc.subject.keywordPlus | MENADIONE 2-METHYL-1,4-NAPHTHOQUINONE | - |
dc.subject.keywordPlus | ISOLATED HEPATOCYTES | - |
dc.subject.keywordPlus | CDC25A PHOSPHATASE | - |
dc.subject.keywordPlus | GROWTH-INHIBITION | - |
dc.subject.keywordPlus | OXIDATIVE STRESS | - |
dc.subject.keywordPlus | P-BENZOQUINONE | - |
dc.subject.keywordPlus | DT-DIAPHORASE | - |
dc.subject.keywordPlus | VITAMIN-K | - |
dc.subject.keywordPlus | EXPRESSION | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Organic | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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