Correlation of VEGF with contrast enhancement on dual-phase dynamic helical CT in liver tumors: Preliminary study
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Kwak, Byung Kook | - |
dc.contributor.author | Shim, Hyung Jin | - |
dc.contributor.author | Park, Eon Sub | - |
dc.contributor.author | Lee, Tae Jin | - |
dc.contributor.author | Paeng, Sung Suk | - |
dc.contributor.author | Lee, Chang Jun | - |
dc.contributor.author | Lim, Hyo K. | - |
dc.contributor.author | Park, Cheol Keun | - |
dc.date.available | 2019-05-30T10:31:25Z | - |
dc.date.issued | 2001-02 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.issn | 1598-6357 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/25244 | - |
dc.description.abstract | The purpose of this preliminary study is to elucidate that vascular endothelial growth factor (VEGF) influences contrast enhancement of hepatic tumors on computed tomography (CT). Fourteen patients with hepatic tumors (11 hepatocellular carcinomas; 3 metastatic cancers) underwent a dual-phase dynamic helical CT or computed tomographic hepatic arteriography, The attenuation of each mass was determined as hyperattenuation, isoattenuation or hypoattenuation with respect to the adjacent nontumorous parenchyma. Gun-needle biopsy was done for each tumor, and paraffin sections were immunostained with anti- VEGF antibody by the avidin-biotin-peroxidase complex method. The pathologic grade was made by intensity (1+, 2+, 3+) and area (+/-, 1+, 2+). The tumor ranged 2.0-14.0 cm in size (mean, 5.8 cm). In arterial phase, the intensity was not correlated with the degree of enhancement (p=0.086). However, the correlation between the attenuation value of hepatic arterial phase and the area of positive tumor cells was statistically significant (p=0.002). VEGF may be the factor that enhances the hepatic mass with water-soluble iodinated contrast agent in CT. | - |
dc.format.extent | 5 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | KOREAN ACAD MEDICAL SCIENCES | - |
dc.title | Correlation of VEGF with contrast enhancement on dual-phase dynamic helical CT in liver tumors: Preliminary study | - |
dc.type | Article | - |
dc.identifier.doi | 10.3346/jkms.2001.16.1.83 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, v.16, no.1, pp 83 - 87 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000167216800015 | - |
dc.identifier.scopusid | 2-s2.0-0035260932 | - |
dc.citation.endPage | 87 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 83 | - |
dc.citation.title | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.citation.volume | 16 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | vascular endothelial growth factor | - |
dc.subject.keywordAuthor | VEGF | - |
dc.subject.keywordAuthor | computed tomography, contrast enhancement | - |
dc.subject.keywordAuthor | liver | - |
dc.subject.keywordAuthor | liver neoplasms | - |
dc.subject.keywordAuthor | liver neoplasms, blood supply | - |
dc.subject.keywordAuthor | computed tomography, helical | - |
dc.subject.keywordPlus | VASCULAR-PERMEABILITY FACTOR | - |
dc.subject.keywordPlus | ENDOTHELIAL GROWTH-FACTOR | - |
dc.subject.keywordPlus | HUMAN BRAIN-TUMORS | - |
dc.subject.keywordPlus | INDUCED ANGIOGENESIS | - |
dc.subject.keywordPlus | FACTOR EXPRESSION | - |
dc.subject.keywordPlus | BREAST-TUMORS | - |
dc.subject.keywordPlus | PURIFICATION | - |
dc.subject.keywordPlus | INHIBITION | - |
dc.subject.keywordPlus | ANTIBODY | - |
dc.relation.journalResearchArea | General & Internal Medicine | - |
dc.relation.journalWebOfScienceCategory | Medicine, General & Internal | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.