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Cited 71 time in webofscience Cited 92 time in scopus
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A new caffeoyl quinic acid from Aster scaber and its inhibitory activity against human immunodeficiency virus-1 (HIV-1) integrase

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dc.contributor.authorKwon, Hak Cheol-
dc.contributor.authorJung, Chil Mann-
dc.contributor.authorShin, Cha Gyun-
dc.contributor.authorLee, Jong Kyo-
dc.contributor.authorChoi, Sang Un-
dc.contributor.authorKim, Sun Yeou-
dc.contributor.authorLee, Kang Ro-
dc.date.available2019-05-30T10:32:09Z-
dc.date.issued2000-11-
dc.identifier.issn0009-2363-
dc.identifier.issn1347-5223-
dc.identifier.urihttps://scholarworks.bwise.kr/cau/handle/2019.sw.cau/25268-
dc.description.abstractThe phytochemical study of the aerial parts of Aster scaber THUNB. (Asteraceae) yielded a new caffeoyl quinic acid, (-) 3,5-dicaffeoyl-muco-quinic acid (2) and three known compounds, (-) 3,5-dicaffeoyl quinic acid (1), (-) 4,5-dicaffeoyl quinic acid (3), (-) 5-caffeoyl quinic acid (4). The structures were established by high resolution spectroscopic methods. The antiviral effects against HIV-1 integrase of the compounds was evaluated. (-) 3,5-Dicaffeoyl-muco-quinic acid (2) exhibited potent antiviral activity with an IC50 value of 7.0 +/- 1.3 mug/ml.-
dc.format.extent3-
dc.language영어-
dc.language.isoENG-
dc.publisherPHARMACEUTICAL SOC JAPAN-
dc.titleA new caffeoyl quinic acid from Aster scaber and its inhibitory activity against human immunodeficiency virus-1 (HIV-1) integrase-
dc.typeArticle-
dc.identifier.doi10.1248/cpb.48.1796-
dc.identifier.bibliographicCitationCHEMICAL & PHARMACEUTICAL BULLETIN, v.48, no.11, pp 1796 - 1798-
dc.description.isOpenAccessN-
dc.identifier.wosid000165110400037-
dc.identifier.scopusid2-s2.0-0033661886-
dc.citation.endPage1798-
dc.citation.number11-
dc.citation.startPage1796-
dc.citation.titleCHEMICAL & PHARMACEUTICAL BULLETIN-
dc.citation.volume48-
dc.type.docTypeArticle-
dc.publisher.location일본-
dc.subject.keywordAuthorAster scaber-
dc.subject.keywordAuthorAsteraceae-
dc.subject.keywordAuthorcaffeoyl quinic acid-
dc.subject.keywordAuthor(-) 3.5-dicaffeoyl-muco-quinic acid-
dc.subject.keywordAuthorHIV-1 integrase-
dc.subject.keywordPlusCONSTITUENTS-
dc.subject.keywordPlusTHUNB-
dc.subject.keywordPlusDERIVATIVES-
dc.subject.keywordPlusPROPOLIS-
dc.relation.journalResearchAreaPharmacology & Pharmacy-
dc.relation.journalResearchAreaChemistry-
dc.relation.journalWebOfScienceCategoryChemistry, Medicinal-
dc.relation.journalWebOfScienceCategoryChemistry, Multidisciplinary-
dc.relation.journalWebOfScienceCategoryPharmacology & Pharmacy-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
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