A new caffeoyl quinic acid from Aster scaber and its inhibitory activity against human immunodeficiency virus-1 (HIV-1) integrase
DC Field | Value | Language |
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dc.contributor.author | Kwon, Hak Cheol | - |
dc.contributor.author | Jung, Chil Mann | - |
dc.contributor.author | Shin, Cha Gyun | - |
dc.contributor.author | Lee, Jong Kyo | - |
dc.contributor.author | Choi, Sang Un | - |
dc.contributor.author | Kim, Sun Yeou | - |
dc.contributor.author | Lee, Kang Ro | - |
dc.date.available | 2019-05-30T10:32:09Z | - |
dc.date.issued | 2000-11 | - |
dc.identifier.issn | 0009-2363 | - |
dc.identifier.issn | 1347-5223 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/25268 | - |
dc.description.abstract | The phytochemical study of the aerial parts of Aster scaber THUNB. (Asteraceae) yielded a new caffeoyl quinic acid, (-) 3,5-dicaffeoyl-muco-quinic acid (2) and three known compounds, (-) 3,5-dicaffeoyl quinic acid (1), (-) 4,5-dicaffeoyl quinic acid (3), (-) 5-caffeoyl quinic acid (4). The structures were established by high resolution spectroscopic methods. The antiviral effects against HIV-1 integrase of the compounds was evaluated. (-) 3,5-Dicaffeoyl-muco-quinic acid (2) exhibited potent antiviral activity with an IC50 value of 7.0 +/- 1.3 mug/ml. | - |
dc.format.extent | 3 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | PHARMACEUTICAL SOC JAPAN | - |
dc.title | A new caffeoyl quinic acid from Aster scaber and its inhibitory activity against human immunodeficiency virus-1 (HIV-1) integrase | - |
dc.type | Article | - |
dc.identifier.doi | 10.1248/cpb.48.1796 | - |
dc.identifier.bibliographicCitation | CHEMICAL & PHARMACEUTICAL BULLETIN, v.48, no.11, pp 1796 - 1798 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000165110400037 | - |
dc.identifier.scopusid | 2-s2.0-0033661886 | - |
dc.citation.endPage | 1798 | - |
dc.citation.number | 11 | - |
dc.citation.startPage | 1796 | - |
dc.citation.title | CHEMICAL & PHARMACEUTICAL BULLETIN | - |
dc.citation.volume | 48 | - |
dc.type.docType | Article | - |
dc.publisher.location | 일본 | - |
dc.subject.keywordAuthor | Aster scaber | - |
dc.subject.keywordAuthor | Asteraceae | - |
dc.subject.keywordAuthor | caffeoyl quinic acid | - |
dc.subject.keywordAuthor | (-) 3.5-dicaffeoyl-muco-quinic acid | - |
dc.subject.keywordAuthor | HIV-1 integrase | - |
dc.subject.keywordPlus | CONSTITUENTS | - |
dc.subject.keywordPlus | THUNB | - |
dc.subject.keywordPlus | DERIVATIVES | - |
dc.subject.keywordPlus | PROPOLIS | - |
dc.relation.journalResearchArea | Pharmacology & Pharmacy | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Medicinal | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Pharmacology & Pharmacy | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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