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Anti-diabetic constituent from the node of lotus rhizome (Nelumbo nucifera Gaertn)
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| DC Field | Value | Language |
|---|---|---|
| dc.contributor.author | Min, W.L. | - |
| dc.contributor.author | Jun, S.K. | - |
| dc.contributor.author | Su, M.C. | - |
| dc.contributor.author | Ji, H.K. | - |
| dc.contributor.author | Jae, S.L. | - |
| dc.date.available | 2019-06-26T01:28:20Z | - |
| dc.date.issued | 2001 | - |
| dc.identifier.issn | 1226-3907 | - |
| dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/26316 | - |
| dc.description.abstract | To investigate anti-diabetic component from the node of lotus rhizome (Nelumbo nucifera; Nymphaeaceae), activity guided isolation was conducted. One amino acid was isolated from active fraction of the aqueous methanolic extract. The structure of this compound was identified as tryptophan (1) by the analysis of spectroscopic evidences and comparisons with the data of authentic samples. Tryptophan reduced the blood glucose level significantly in glucose-fed hyperglycemic mice compared with glucose-treated group and exhibited 44.3% of activity compared with tolbutamide. | - |
| dc.format.extent | 3 | - |
| dc.language | 영어 | - |
| dc.language.iso | ENG | - |
| dc.title | Anti-diabetic constituent from the node of lotus rhizome (Nelumbo nucifera Gaertn) | - |
| dc.type | Article | - |
| dc.identifier.bibliographicCitation | Natural Product Sciences, v.7, no.4, pp 107 - 109 | - |
| dc.description.isOpenAccess | N | - |
| dc.identifier.scopusid | 2-s2.0-0035723132 | - |
| dc.citation.endPage | 109 | - |
| dc.citation.number | 4 | - |
| dc.citation.startPage | 107 | - |
| dc.citation.title | Natural Product Sciences | - |
| dc.citation.volume | 7 | - |
| dc.type.docType | Article | - |
| dc.publisher.location | 대한민국 | - |
| dc.subject.keywordAuthor | Anti-diabetic activity | - |
| dc.subject.keywordAuthor | Nelumbo nucifera | - |
| dc.subject.keywordAuthor | Tryptophan | - |
| dc.subject.keywordPlus | antidiabetic agent | - |
| dc.subject.keywordPlus | glucose | - |
| dc.subject.keywordPlus | nelumbo nucifera extract | - |
| dc.subject.keywordPlus | plant extract | - |
| dc.subject.keywordPlus | tolbutamide | - |
| dc.subject.keywordPlus | tryptophan | - |
| dc.subject.keywordPlus | unclassified drug | - |
| dc.subject.keywordPlus | animal experiment | - |
| dc.subject.keywordPlus | animal model | - |
| dc.subject.keywordPlus | article | - |
| dc.subject.keywordPlus | controlled study | - |
| dc.subject.keywordPlus | drug isolation | - |
| dc.subject.keywordPlus | drug potency | - |
| dc.subject.keywordPlus | glucose blood level | - |
| dc.subject.keywordPlus | hyperglycemia | - |
| dc.subject.keywordPlus | male | - |
| dc.subject.keywordPlus | mouse | - |
| dc.subject.keywordPlus | nonhuman | - |
| dc.subject.keywordPlus | rhizome | - |
| dc.subject.keywordPlus | structure activity relation | - |
| dc.description.journalRegisteredClass | scopus | - |
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