Development of a Point-of-Care Testing Platform With a Nanogap-Embedded Separated Double-Gate Field Effect Transistor Array and Its Readout System for Detection of Avian Influenza
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Im, Maesoon | - |
dc.contributor.author | Ahn, Jae-Hyuk | - |
dc.contributor.author | Han, Jin-Woo | - |
dc.contributor.author | Park, Tae Jung | - |
dc.contributor.author | Lee, Sang Yup | - |
dc.contributor.author | Choi, Yang-Kyu | - |
dc.date.available | 2019-07-11T01:56:16Z | - |
dc.date.issued | 2011-02 | - |
dc.identifier.issn | 1530-437X | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/27730 | - |
dc.description.abstract | Label-free electrical detection of avian influenza (AI) is demonstrated for the development of a point-of-care testing (POCT) platform. For a new POCT platform, a novel field effect transistor (FET)-based biosensor array was fabricated with conventional complementary metal-oxide-semiconductor (CMOS) technology. Nanogap-embedded separated double-gate FETs (nanogap-DGFETs) were realized in a 6 x 6 array as a biosensor cartridge. Moreover, the low-noise readout circuit was designed and fabricated using a 0.35-mu m standard CMOS process. The AI antigen and antibody were bound with the aid of silica-binding proteins (SBP) in the nanogap of the biosensor device. Because the gate dielectric constant was increased by the immobilized biomolecules, the threshold voltage of the nanogap-DGFET was reduced while the drain-to-source current was enhanced. Drain-to-source currents of the nanogap-DGFET array were successfully acquired using the fabricated readout circuitry and measurement setup. This platform is suitable for a simple and effective label-free detection of AI in POCT applications. | - |
dc.format.extent | 10 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC | - |
dc.title | Development of a Point-of-Care Testing Platform With a Nanogap-Embedded Separated Double-Gate Field Effect Transistor Array and Its Readout System for Detection of Avian Influenza | - |
dc.type | Article | - |
dc.identifier.doi | 10.1109/JSEN.2010.2062502 | - |
dc.identifier.bibliographicCitation | IEEE SENSORS JOURNAL, v.11, no.2, pp 351 - 360 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000284364500012 | - |
dc.identifier.scopusid | 2-s2.0-78649264150 | - |
dc.citation.endPage | 360 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 351 | - |
dc.citation.title | IEEE SENSORS JOURNAL | - |
dc.citation.volume | 11 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | Avian influenza (AI) | - |
dc.subject.keywordAuthor | biosensor | - |
dc.subject.keywordAuthor | field-effect transistor (FET) | - |
dc.subject.keywordAuthor | nanogap | - |
dc.subject.keywordAuthor | point-of-care testing (POCT) | - |
dc.subject.keywordAuthor | silica-binding proteins (SBP) | - |
dc.subject.keywordPlus | BLOOD ANALYSIS | - |
dc.subject.keywordPlus | ANTIBODY | - |
dc.subject.keywordPlus | VIRUS | - |
dc.subject.keywordPlus | BIOSENSORS | - |
dc.subject.keywordPlus | SENSORS | - |
dc.subject.keywordPlus | PROTEIN | - |
dc.relation.journalResearchArea | Engineering | - |
dc.relation.journalResearchArea | Instruments & Instrumentation | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Engineering, Electrical & Electronic | - |
dc.relation.journalWebOfScienceCategory | Instruments & Instrumentation | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.