A Dual-Gate Field-Effect Transistor for Label-Free Electrical Detection of Avian Influenza
DC Field | Value | Language |
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dc.contributor.author | Kim, Jee-Yeon | - |
dc.contributor.author | Ahn, Jae-Hyuk | - |
dc.contributor.author | Moon, Dong-Il | - |
dc.contributor.author | Kim, Sungho | - |
dc.contributor.author | Park, Tae Jung | - |
dc.contributor.author | Lee, Sang Yup | - |
dc.contributor.author | Choi, Yang-Kyu | - |
dc.date.available | 2019-07-11T02:56:16Z | - |
dc.date.issued | 2012-03 | - |
dc.identifier.issn | 2191-1630 | - |
dc.identifier.issn | 2191-1649 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/27768 | - |
dc.description.abstract | A dual-gate silicon nanowire field-effect transistor (FET) fabricated on a bulk substrate is designed to perform label-free electrical detection of the avian influenza antibody. A region of a FET channel that is conventionally covered by a gate electrode is intentionally left open in the dual-gate configuration, to provide a binding site for biological species. As a result, the channel potential at this open area is affected by the polarity and charge of the biological species that binds to the opened channel. The proposed device can be used as a biosensor by comparing its electrical characteristics before and after exposing the device to biological species of interest. This detection mechanism is verified using numerical simulation and by attaching charged polyelectrolytes (PAH and PSS) to the opened channel. Additionally, the avian influenza antibody is successfully detected without a labeling step using the proposed dual-gate FET. As a biomedical diagnostic tool, the proposed biosensor offers the advantages of label-free detection capability, low-cost compatibility with the complementary metal-oxide semiconductor fabrication process, and a read-out system for on-chip integration. © 2012 Springer Science+Business Media, LLC. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.title | A Dual-Gate Field-Effect Transistor for Label-Free Electrical Detection of Avian Influenza | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s12668-011-0035-0 | - |
dc.identifier.bibliographicCitation | BioNanoScience, v.2, no.1, pp 35 - 41 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.scopusid | 2-s2.0-84862991592 | - |
dc.citation.endPage | 41 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 35 | - |
dc.citation.title | BioNanoScience | - |
dc.citation.volume | 2 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | Avian influenza | - |
dc.subject.keywordAuthor | Biosensor | - |
dc.subject.keywordAuthor | Dual-gate | - |
dc.subject.keywordAuthor | Field-effect transistor | - |
dc.subject.keywordAuthor | Label-free | - |
dc.subject.keywordPlus | Avian influenza | - |
dc.subject.keywordPlus | Bio medical diagnostics | - |
dc.subject.keywordPlus | Biological species | - |
dc.subject.keywordPlus | Bulk substrates | - |
dc.subject.keywordPlus | Channel potential | - |
dc.subject.keywordPlus | Charged polyelectrolytes | - |
dc.subject.keywordPlus | Complementary metal oxide semiconductors | - |
dc.subject.keywordPlus | Detection mechanism | - |
dc.subject.keywordPlus | Dual-gate | - |
dc.subject.keywordPlus | Dual-gate FET | - |
dc.subject.keywordPlus | Electrical characteristic | - |
dc.subject.keywordPlus | Electrical detection | - |
dc.subject.keywordPlus | Gate electrodes | - |
dc.subject.keywordPlus | Label free | - |
dc.subject.keywordPlus | Label-free detection | - |
dc.subject.keywordPlus | Labeling steps | - |
dc.subject.keywordPlus | On-chip integration | - |
dc.subject.keywordPlus | Silicon nanowire field-effect transistors | - |
dc.subject.keywordPlus | Antibodies | - |
dc.subject.keywordPlus | Biosensors | - |
dc.subject.keywordPlus | Field effect transistors | - |
dc.subject.keywordPlus | Chemical detection | - |
dc.description.journalRegisteredClass | scopus | - |
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