Graphene-based electrochemical biosensor for pathogenic virus detection
DC Field | Value | Language |
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dc.contributor.author | Liu, Fei | - |
dc.contributor.author | Choi, Ki Seok | - |
dc.contributor.author | Park, Tae Jung | - |
dc.contributor.author | Lee, Sang Yup | - |
dc.contributor.author | Seo, Tae Seok | - |
dc.date.available | 2019-07-11T02:56:29Z | - |
dc.date.issued | 2011-06 | - |
dc.identifier.issn | 1976-0280 | - |
dc.identifier.issn | 2092-7843 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/27776 | - |
dc.description.abstract | A graphene based biosensor system is presented for performing highly sensitive pathogenic virus detection. A free-standing conductive graphene film was prepared as a novel electrochemical sensor through two steps: synthesis of a graphene oxide (GO) film from GO colloidal suspensions by using a speed vacuum concentrator and thermal annealing process at 900 degrees C with H(2)/Ar flow to generate a reduced GO film. The resultant graphene film shows an excellent electron transfer property on the surface in the [Fe(CN)(6)](3-)/(4-) redox system and is used as a working electrode in the electrochemical biosensor. The surface of graphene is modified with pyrene derivatives, and then covalently linked with virus-specific antibodies. The target cell, rotavirus, is captured on the graphene film through antibody-antigen interaction, and the entire process was monitored by cyclic voltammetric responses. A 10(5) pfu/mL of input cells is detected with ca. 30.7% sensitivity, and ca. 1.3% sensitivity is measured with 10(3) pfu/mL of input cells, demonstrating that graphene film based electrode can be applied for electrochemical biosensor. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | SPRINGER | - |
dc.title | Graphene-based electrochemical biosensor for pathogenic virus detection | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s13206-011-5204-2 | - |
dc.identifier.bibliographicCitation | BIOCHIP JOURNAL, v.5, no.2, pp 123 - 128 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000291665500004 | - |
dc.identifier.scopusid | 2-s2.0-79958794063 | - |
dc.citation.endPage | 128 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 123 | - |
dc.citation.title | BIOCHIP JOURNAL | - |
dc.citation.volume | 5 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | Graphene film | - |
dc.subject.keywordAuthor | Electrochemical biosensor | - |
dc.subject.keywordAuthor | Pathogen detection | - |
dc.subject.keywordAuthor | Detection sensitivity | - |
dc.subject.keywordPlus | CARBON NANOTUBES | - |
dc.subject.keywordPlus | FILMS | - |
dc.subject.keywordPlus | OXIDE | - |
dc.subject.keywordPlus | FLUORESCENCE | - |
dc.subject.keywordPlus | SHEETS | - |
dc.relation.journalResearchArea | Biochemistry & Molecular Biology | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalWebOfScienceCategory | Biochemical Research Methods | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Analytical | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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