백출 지상부의 항산화 성분

Abstract

Atractylodes macrocephala has been used for renal anorexia, gastroenteritis, cold, dyspepsia in Korean folk med-icine. Specially aerial parts has been eaten as edible mountain herbs. In order to investigate the efficacy of antioxidant activ-ity, the activity guided fractionation and isolation of physiologically active substance were performed. For the investigationof the active components from Atractylodes macrocephala MeOH extracts of aerial parts of Atractylodes macrocephala Koid-zumi L. were suspended with H2O, partitioned by CHCl3. In order to investigate the efficacy of antioxidative activity, the3, H2O, 30% MeOH, 60%MeOH, MeOH fractions were examined antioxidative activity by DPPH method. It was revealed that 30% MeOH and 60%MeOH fractions have significantly antioxidant activity. From 30% MeOH and 60% MeOH fraction, six flavonoids (7-meth-oxy-pinocembrin-7-O-β-D-glucopyranoside, apigenin-8-C-β-D-glucopyranoside, 4'-caffeoyl-luteolin-6-glucopyranoside, lute-loin-6-C-β-D-glucopyranoside, apigenin-6-C-β-D-glucopyranoside, luteolin) and four phenylpropanoids (3-feruloylquinicacid, 4,5-di-O-caffeoylquinic acid, feruloyl acid, 3,5-di-O-caffeoylquinic acid) were isolated. To investigate the antioxidanton low density lipoprotein (LDL) with TBARS asay. Six compounds (III, IV, V, VI, IX, X) which have antioxidant factorshowed significant activities.Keywords . Atractylodes macrocephala, DPPH method, TBARS asay, anti-lipid peroxidation.. (Atractylodes macrocephala Koidzumi). ... (Com-positae). ... ... ..... ...... ......... .. ... .. , .. , ...... .... ..