2-치환 플라본 유도체의 합성
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 단온화 | - |
dc.contributor.author | 김수진 | - |
dc.contributor.author | 임채욱 | - |
dc.date.available | 2019-07-24T03:59:16Z | - |
dc.date.issued | 2006 | - |
dc.identifier.issn | 0377-9556 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/30291 | - |
dc.description.abstract | Flavone was found to inhibit tyrosinase and reduce synthesis of melanin to show skin-lightening effect. Withthe hope of identifying skin-lightening flavones, we synthesized flavone analogs. Substituted benzoic acids (1) were treatedwith oxalyl chloride in DMF to yield benzoyl chlorides (2), which were reacted with 2-hydroxyacetophenones (3) to aford2-benzoyloxyacetophenones (4). These acetophenones (4) were converted into 1,3-diketones (5) with base and then treatedwith acid to give flavone derivatives (6).Keywords . | - |
dc.format.extent | 5 | - |
dc.publisher | 대한약학회 | - |
dc.title | 2-치환 플라본 유도체의 합성 | - |
dc.title.alternative | Synthesis of 2-Substituted Flavone Derivatives | - |
dc.type | Article | - |
dc.identifier.bibliographicCitation | 약 학 회 지, v.50, no.6, pp 398 - 402 | - |
dc.identifier.kciid | ART001043063 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | 402 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 398 | - |
dc.citation.title | 약 학 회 지 | - |
dc.citation.volume | 50 | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | flavone | - |
dc.subject.keywordAuthor | tyrosinase inhibitors | - |
dc.description.journalRegisteredClass | kci | - |
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