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2-치환 플라본 유도체의 합성

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dc.contributor.author단온화-
dc.contributor.author김수진-
dc.contributor.author임채욱-
dc.date.available2019-07-24T03:59:16Z-
dc.date.issued2006-
dc.identifier.issn0377-9556-
dc.identifier.urihttps://scholarworks.bwise.kr/cau/handle/2019.sw.cau/30291-
dc.description.abstractFlavone was found to inhibit tyrosinase and reduce synthesis of melanin to show skin-lightening effect. Withthe hope of identifying skin-lightening flavones, we synthesized flavone analogs. Substituted benzoic acids (1) were treatedwith oxalyl chloride in DMF to yield benzoyl chlorides (2), which were reacted with 2-hydroxyacetophenones (3) to aford2-benzoyloxyacetophenones (4). These acetophenones (4) were converted into 1,3-diketones (5) with base and then treatedwith acid to give flavone derivatives (6).Keywords .-
dc.format.extent5-
dc.publisher대한약학회-
dc.title2-치환 플라본 유도체의 합성-
dc.title.alternativeSynthesis of 2-Substituted Flavone Derivatives-
dc.typeArticle-
dc.identifier.bibliographicCitation약 학 회 지, v.50, no.6, pp 398 - 402-
dc.identifier.kciidART001043063-
dc.description.isOpenAccessN-
dc.citation.endPage402-
dc.citation.number6-
dc.citation.startPage398-
dc.citation.title약 학 회 지-
dc.citation.volume50-
dc.publisher.location대한민국-
dc.subject.keywordAuthorflavone-
dc.subject.keywordAuthortyrosinase inhibitors-
dc.description.journalRegisteredClasskci-
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