대장암에서 CD31과 D2-40 발현에 의한 혈관성 및 림프관성 미세혈관 밀도 측정
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 윤상인 | - |
dc.contributor.author | 김범규 | - |
dc.contributor.author | 차성재 | - |
dc.contributor.author | 박성준 | - |
dc.contributor.author | 장인택 | - |
dc.contributor.author | 박성일 | - |
dc.contributor.author | 이태진 | - |
dc.date.available | 2019-07-29T02:57:26Z | - |
dc.date.issued | 2007-10 | - |
dc.identifier.issn | 2288-6575 | - |
dc.identifier.issn | 2288--679 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/30515 | - |
dc.description.abstract | Purpose: Angiogenesis and lymphangiogenesis play important roles in the growth, progression and metastasis of colon cancer. We performed this study in order to investigate the significance of the CD31 and D2-40 expressions as prognostic factors in colon cancer. Methods: The angiogenic and lymphagiogenic microvessel density was assessed by immunohistochemical staining of CD31 and D2-40 on samples that were resected from 66 patients with colorectal cancer. Results: Strong correlation was observed between the CD31 microvessel density and being positive for having tumor emboli and lymph node metastasis (P=0.001, P=0.003). The D2-40 lymphatic vessel density was correlated with being positive for having tumor emboli (P=0.0001), the depth of invasion (P=0.0001), lymph node metastasis (P= 0.0001) and the cancer stage (P=0.0001). The D2-40 lymphatic vessel density was also correlated with the CD31 count (P=0.003). Conclusion: These results suggested that the CD31 and D2-40 expressions are useful predictors of lymph node metastasis and they are prognostic factors for colon cancer. (J Korean Surg Soc 2007;73:315-320) | - |
dc.format.extent | 6 | - |
dc.language | 한국어 | - |
dc.language.iso | KOR | - |
dc.publisher | 대한외과학회 | - |
dc.title | 대장암에서 CD31과 D2-40 발현에 의한 혈관성 및 림프관성 미세혈관 밀도 측정 | - |
dc.title.alternative | Angiogenic and Lymphangiogenic Microvessel Density in Terms of the Expression of CD31 and D2-40 in Colon Cancer | - |
dc.type | Article | - |
dc.identifier.bibliographicCitation | 대한외과학회지, v.73, no.4, pp 315 - 320 | - |
dc.identifier.kciid | ART001092619 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | 320 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 315 | - |
dc.citation.title | 대한외과학회지 | - |
dc.citation.volume | 73 | - |
dc.identifier.url | https://www.dbpia.co.kr/journal/articleDetail?nodeId=NODE01894990 | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | 대장암 | - |
dc.subject.keywordAuthor | 혈관신생 | - |
dc.subject.keywordAuthor | 림프관 신생 | - |
dc.subject.keywordAuthor | Colon cancer | - |
dc.subject.keywordAuthor | CD31 | - |
dc.subject.keywordAuthor | D2-40 | - |
dc.subject.keywordAuthor | Angiogenesis | - |
dc.subject.keywordAuthor | Lymphangiogenesis | - |
dc.description.journalRegisteredClass | kci | - |
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