Magnitude of Mycobacterium tuberculosis transmission among household and non-household contacts of TB patients
DC Field | Value | Language |
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dc.contributor.author | Kato-Maeda, M. | - |
dc.contributor.author | Choi, J.C. | - |
dc.contributor.author | Jarlsberg, L.G. | - |
dc.contributor.author | Grinsdale, J.A. | - |
dc.contributor.author | Higashi, J. | - |
dc.contributor.author | Kawamura, L.M. | - |
dc.contributor.author | Osmond, D.H. | - |
dc.contributor.author | Hopewell, P.C. | - |
dc.date.available | 2019-08-13T05:59:59Z | - |
dc.date.issued | 2019-04 | - |
dc.identifier.issn | 1027-3719 | - |
dc.identifier.issn | 1815-7920 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/33154 | - |
dc.description.abstract | SETTING: The household and non-household contacts of patients with tuberculosis (TB) face varying degrees of risk of infection by Mycobacterium tuberculosis. OBJECTIVE : To quantify new infection and to determine the risk factors associated with new infection among named contacts in San Francisco, CA, USA. DESIGN: We performed a cohort study in patients with culture-positive pulmonary TB. We analyzed patient, contact, environmental and bacterial characteristics. RESULTS : Of the 2422 contacts named by 256 patients, 149 (6.2%) had new infection due to recent transmission from 79 (30.9%) patients. Of the 149 new infections, 87 (58.4%) occurred among household contacts and 62 (41.6%) among non-household contacts. Numerous acid-fast bacilli in sputum (odds ratio [OR] 2.64, 95%CI 1.32-5.25) and contacts being named by more than one patient (OR 2.90, 95%CI 1.23-6.85) were associated with new infection among household contacts. Being older than 50 years (OR 1.93, 95%CI 1.09- 3.41) and an Asian/Pacific Islander (OR 3.09, 95%CI 1.50-6.37) were associated with new infection among non-household contacts. CONC L U S IONS : Fewer than one third of patients caused new infection to his/her contacts. A substantial proportion of transmission resulting in new infection occurred outside of the household. The risk factors for infection among household and non-household contacts are different and should be considered when prioritizing control interventions. © 2019 The Union. | - |
dc.format.extent | 8 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | International Union against Tubercul. and Lung Dis. | - |
dc.title | Magnitude of Mycobacterium tuberculosis transmission among household and non-household contacts of TB patients | - |
dc.type | Article | - |
dc.identifier.doi | 10.5588/ijtld.18.0273 | - |
dc.identifier.bibliographicCitation | International Journal of Tuberculosis and Lung Disease, v.23, no.4, pp 433 - 440 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000467710200010 | - |
dc.identifier.scopusid | 2-s2.0-85065759851 | - |
dc.citation.endPage | 440 | - |
dc.citation.number | 4 | - |
dc.citation.startPage | 433 | - |
dc.citation.title | International Journal of Tuberculosis and Lung Disease | - |
dc.citation.volume | 23 | - |
dc.type.docType | Article | - |
dc.publisher.location | 프랑스 | - |
dc.subject.keywordAuthor | contact investigation | - |
dc.subject.keywordAuthor | risk factors | - |
dc.subject.keywordPlus | ACTIVE TUBERCULOSIS | - |
dc.subject.keywordPlus | INFECTION | - |
dc.subject.keywordPlus | YIELD | - |
dc.subject.keywordPlus | COMMUNITY | - |
dc.subject.keywordPlus | COUNTRIES | - |
dc.subject.keywordPlus | OUTCOMES | - |
dc.relation.journalResearchArea | Infectious Diseases | - |
dc.relation.journalResearchArea | Respiratory System | - |
dc.relation.journalWebOfScienceCategory | Infectious Diseases | - |
dc.relation.journalWebOfScienceCategory | Respiratory System | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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