Estrogenic Xenobiotics가 돼지 정자의 운동성 및 운동역학에 미치는 영향
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 오신애 | - |
dc.contributor.author | 박유진 | - |
dc.contributor.author | 송원희 | - |
dc.contributor.author | El-Sayed A. Mohamed | - |
dc.contributor.author | 방명걸 | - |
dc.date.available | 2019-08-21T06:04:30Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1738-2432 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/35040 | - |
dc.description.abstract | Endocrine disruptors bind to hormone receptors on sperm membrane, therefore spermatozoa are potentially a useful model for examining estrogenic activities of endocrine disruptors. The objective of this study was to compare the effects of two xenoestrogenic compounds [genistein (Gen) and 4-tert-octylphenol (OP)] to those of two steroids [estrogen (E2) and progesterone (P4)] on boar sperm % motility and motion kinematics of in vitro. Porcine spermatozoa were incubated with various concentrations (0.001~100 μM) of each chemical for 15 or 30 min, and then assessed % motility and sperm motion kinematics using computer assisted sperm analyzer (CASA). Each chemical decreased sperm % motility, and OP decreased VSL and VAP compared with untreated control(p<0.05). E2 stimulated the motion kinematic changes except VCL. Moreover, Gen had effects on VCL and VAP alterations after 30 min incubation. In summary, since all chemicals studied effectively altered sperm % motility and motion kinematics, it was concluded that porcine spermatozoa could be a useful model for in vitro screening of potential endocrine disruptors. | - |
dc.format.extent | 8 | - |
dc.publisher | 한국동물번식학회 | - |
dc.title | Estrogenic Xenobiotics가 돼지 정자의 운동성 및 운동역학에 미치는 영향 | - |
dc.title.alternative | Effect of Estrogenic Xonibiotics on Boar Sperm Motility and Motion Kinematics | - |
dc.type | Article | - |
dc.identifier.bibliographicCitation | Reproductive & Developmental biology, v.35, no.1, pp 47 - 54 | - |
dc.identifier.kciid | ART001544288 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | 54 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 47 | - |
dc.citation.title | Reproductive & Developmental biology | - |
dc.citation.volume | 35 | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Boar spermatozoa | - |
dc.subject.keywordAuthor | Endocrine disruptors | - |
dc.subject.keywordAuthor | Xenobiotics | - |
dc.subject.keywordAuthor | Motility | - |
dc.subject.keywordAuthor | Motion kinematics | - |
dc.description.journalRegisteredClass | kci | - |
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