식방풍의 성분분리 및 생리활성
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김도훈 | - |
dc.contributor.author | 한지수 | - |
dc.contributor.author | 김기은 | - |
dc.contributor.author | 김진효 | - |
dc.contributor.author | 김성건 | - |
dc.contributor.author | 김호경 | - |
dc.contributor.author | 오오진 | - |
dc.contributor.author | 황완균 | - |
dc.date.available | 2019-08-28T10:06:35Z | - |
dc.date.issued | 2009 | - |
dc.identifier.issn | 0377-9556 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/36297 | - |
dc.description.abstract | In this study, isolation of antioxidative compounds was performed for development of anti-oxidizing agent. CHCl3, H2O, 30%, 60% MeOH, MeOH fractions were examined antioxidative activity by DPPH, test of inhibition on NO production. It was revealed that 30%, 60% MeOH and CHCl3 fractions had significant antioxidative activity. In 30% MeOH and 60% MeOH, CHCl3 fraction, six compounds were isolated and elucidated as adenosine(Ⅰ), guanosine(Ⅱ), peucedanol 7- O-β-D-apiofuranosyl(1→6)-β-glucopyranoside(Ⅲ), peucedanol 7-O-β-D-glucopyranoside(Ⅳ), peucedanol(Ⅴ) and scopoletin(Ⅵ) by physicochemical data and spectroscopic methods. (Negative FAB-MS, 1H-NMR, 13C-NMR). The results from antioxidative activity screening for the each compound showed that compound Ⅵ was relatively superior antioxidant ability. In anti-inflammatory activation assay, compound Ⅲ, Ⅳ, Ⅵ had concentration-dependent-activity and compound Ⅳ had superior anti-inflammatory ability. These results suggest that Peucedani Radix might be developed as a potent anti-oxidative, antiinflammatory agents and ingredients for related functional foods. | - |
dc.format.extent | 8 | - |
dc.publisher | 대한약학회 | - |
dc.title | 식방풍의 성분분리 및 생리활성 | - |
dc.title.alternative | Biolosical Activities of Isolated Compounds from Peucedani Radix | - |
dc.type | Article | - |
dc.identifier.bibliographicCitation | 약 학 회 지, v.53, no.3, pp 130 - 137 | - |
dc.identifier.kciid | ART001352622 | - |
dc.description.isOpenAccess | N | - |
dc.citation.endPage | 137 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 130 | - |
dc.citation.title | 약 학 회 지 | - |
dc.citation.volume | 53 | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Peucedani Radix | - |
dc.subject.keywordAuthor | antioxidative effect | - |
dc.subject.keywordAuthor | Peucedanum japonicum | - |
dc.description.journalRegisteredClass | kci | - |
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