A randomized, patient/evaluator-blinded, split-face study to compare the efficacy and safety of polycaprolactone and polynucleotide fillers in the correction of crow's feet: The latest biostimulatory dermal filler for crow's feet
DC Field | Value | Language |
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dc.contributor.author | Jeong, G.J. | - |
dc.contributor.author | Ahn, G.R. | - |
dc.contributor.author | Park, S.J. | - |
dc.contributor.author | Hong, J.Y. | - |
dc.contributor.author | Kim, B.J. | - |
dc.date.available | 2020-04-03T00:55:52Z | - |
dc.date.issued | 2020-07 | - |
dc.identifier.issn | 1473-2130 | - |
dc.identifier.issn | 1473-2165 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/37873 | - |
dc.description.abstract | Background: No data on the clinical results and safety profiles of the polycaprolactone (PCL) -based dermal filler for crow's feet correction have been published. Aims: This study was designed to compare the efficacy and safety of a novel PCL-based dermal filler, DLMR01, with that of RJR, a purified polynucleotide dermal filler. Patients/Methods: A total of 30 subjects with symmetric crow's feet of 2-4 points on the Crow's Feet Grading Scale (CFGS) were enrolled in this randomized, patient/evaluator-blinded, split-face study. Each subject was randomized to receive injections of DLMR01 or RJR in their right or left crow's feet. At 4 and 12 weeks, all participants were evaluated via CFGS, Global Aesthetic Improvement Scale (GAIS), and PRIMOS software system. Results: No significant difference in CFGS, GAIS, and Ra value was detected between DLMR01 side and RJR at 12 weeks (improvement rate in CFGS from baseline at week 12—DLMR01: 48.28% [14/29], RJR: 41.38% [12/29]). Conclusion: The novel PCL-based dermal filler DLMR01 shows suitable efficacy and safety, widening the selection possibilities for clinicians and patients in the treatment crow's feet. © 2019 Wiley Periodicals, Inc. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | Blackwell Publishing Ltd | - |
dc.title | A randomized, patient/evaluator-blinded, split-face study to compare the efficacy and safety of polycaprolactone and polynucleotide fillers in the correction of crow's feet: The latest biostimulatory dermal filler for crow's feet | - |
dc.type | Article | - |
dc.identifier.doi | 10.1111/jocd.13199 | - |
dc.identifier.bibliographicCitation | Journal of Cosmetic Dermatology, v.19, no.7, pp 1593 - 1599 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000541230800010 | - |
dc.identifier.scopusid | 2-s2.0-85074789917 | - |
dc.citation.endPage | 1599 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 1593 | - |
dc.citation.title | Journal of Cosmetic Dermatology | - |
dc.citation.volume | 19 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | biostimulatory | - |
dc.subject.keywordAuthor | crow's feet | - |
dc.subject.keywordAuthor | dermal filler | - |
dc.subject.keywordAuthor | polycaprolactone | - |
dc.subject.keywordAuthor | polynucleotide | - |
dc.relation.journalResearchArea | Dermatology | - |
dc.relation.journalWebOfScienceCategory | Dermatology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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