Efficacy and Safety of High-Intensity Focused Ultrasound for Noninvasive Abdominal Subcutaneous Fat Reduction
- Authors
- Hong J.Y.; Ko E.J.; Choi S.Y.; Kwon T.-R.; Kim J.H.; Kim S.Y.; Kim B.J.
- Issue Date
- Feb-2020
- Publisher
- NLM (Medline)
- Citation
- Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], v.46, no.2, pp 213 - 219
- Pages
- 7
- Journal Title
- Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]
- Volume
- 46
- Number
- 2
- Start Page
- 213
- End Page
- 219
- URI
- https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/37936
- DOI
- 10.1097/DSS.0000000000002016
- ISSN
- 1524-4725
1524-4725
- Abstract
- BACKGROUND: Demand for noninvasive body contouring has increased. OBJECTIVE: We evaluated the efficacy and safety of a thermal high-intensity focused ultrasound (HIFU) device for abdominal body shaping. PATIENTS AND METHODS: Adults with a body mass index ≤30 kg/m and an abdominal subcutaneous fat tissue thickness ≥2.5 cm were enrolled for HIFU treatment at energy levels of 150 J/cm (first session) and 135 J/cm (second session). The primary end point was a change from baseline waist circumference at post-treatment Week 8. Secondary efficacy end points were: changes in body weight, waist/hip ratio, and fat thickness assessed by ultrasound, caliper, and a fat CT scan. The Global Aesthetic Improvement Scale was evaluated by both investigators and subjects. RESULTS: The primary assessment achieved statistical significance, showing a reduction of 3.43 cm in mean waist circumference. The treatment effect was cumulative, with a steady decrease in waist circumference and fat thickness. The mean pain scores immediately after treatment were 4.45 ± 2.74 on a scale of 1 to 10 with 10 being the most painful, which decreased to 1.10 ± 1.33 after 1 week. CONCLUSION: High-intensity focused ultrasound is an effective and safe treatment modality for reducing waist circumference in nonobese individuals with focal fat accumulation.
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