Integration of Optical Applicator With Balloon Catheter for Photothermal Treatment of Biliary Stricture
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Bak, Jinoh | - |
dc.contributor.author | Hwang, Jieun | - |
dc.contributor.author | Park, Suhyun | - |
dc.contributor.author | Kang, Hyun Wook | - |
dc.date.available | 2019-03-08T07:56:11Z | - |
dc.date.issued | 2017-10 | - |
dc.identifier.issn | 0196-8092 | - |
dc.identifier.issn | 1096-9101 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/3819 | - |
dc.description.abstract | Background and Objective: Bile duct stricture is an uncommon disease in gastroenterology resulting from postoperative trauma. In spite of non-surgical treatments, clinical outcomes for the biliary strictures still encounter high restenosis and stent migration. The objective of the current study was to investigate the feasible application of a balloon catheter-integrated diffing applicator to thermally treat the bile duct stricture. Materials and Methods: 400-mm optical fibers were micro-machined and then integrated with an inflatable balloon catheter. The fabricated applicator was tested on porcine bile ducts with 20-W 980 nm laser light for 60 s, and a thermal camera was used to measure thermal response of the tissue. Due to mechanical pressure, the inflated balloon was able to expand the tissue lumen up to 6 mm in diameter. Results: Compared to control, the inner area of the treated tissue was increased by four fold (i.e., 2.74 +/- 0.05 mm2 for treated vs. 0.73 +/- 0.14 mm2 for control) during the balloon catheter-assisted laser irradiation. The laser-induced tissue temperature reached up to 80.1 +/- 6.4 degrees C (thermal gradient = 1.2 degrees C/s). A thin layer of coagulation necrosis (0.5 +/- 0.1 mm) consistently formed around the lumen. Conclusion: The proposed balloon catheter-integrated diffusing applicator can be a feasible minimally invasive device to photothermally treat the obstructive bile ducts. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | WILEY | - |
dc.title | Integration of Optical Applicator With Balloon Catheter for Photothermal Treatment of Biliary Stricture | - |
dc.type | Article | - |
dc.identifier.doi | 10.1002/lsm.22688 | - |
dc.identifier.bibliographicCitation | LASERS IN SURGERY AND MEDICINE, v.49, no.8, pp 781 - 786 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000411028000008 | - |
dc.identifier.scopusid | 2-s2.0-85029572617 | - |
dc.citation.endPage | 786 | - |
dc.citation.number | 8 | - |
dc.citation.startPage | 781 | - |
dc.citation.title | LASERS IN SURGERY AND MEDICINE | - |
dc.citation.volume | 49 | - |
dc.type.docType | Article | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | balloon catheter | - |
dc.subject.keywordAuthor | bile duct | - |
dc.subject.keywordAuthor | optical diffuser | - |
dc.subject.keywordAuthor | photothermal treatment | - |
dc.subject.keywordAuthor | tissue stricture | - |
dc.subject.keywordPlus | BILE-DUCT STRICTURES | - |
dc.subject.keywordPlus | METAL STENTS | - |
dc.subject.keywordPlus | ANGIOPLASTY | - |
dc.subject.keywordPlus | IRRADIATION | - |
dc.subject.keywordPlus | OBSTRUCTION | - |
dc.subject.keywordPlus | TRIAL | - |
dc.relation.journalResearchArea | Dermatology | - |
dc.relation.journalResearchArea | Surgery | - |
dc.relation.journalWebOfScienceCategory | Dermatology | - |
dc.relation.journalWebOfScienceCategory | Surgery | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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