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Parabens in breast milk and possible sources of exposure among lactating women in Korea

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dc.contributor.authorPark, Na-Youn-
dc.contributor.authorCho, Yoon Hee-
dc.contributor.authorChoi, Kyungho-
dc.contributor.authorLee, Eun-Hee-
dc.contributor.authorKim, Yang Jee-
dc.contributor.authorKim, Jung Hoan-
dc.contributor.authorKho, Younglim-
dc.date.available2020-04-17T04:22:11Z-
dc.date.issued2019-12-
dc.identifier.issn0269-7491-
dc.identifier.issn1873-6424-
dc.identifier.urihttps://scholarworks.bwise.kr/cau/handle/2019.sw.cau/38630-
dc.description.abstractParabens, broad-spectrum antimicrobial preservatives widely used in various consumer products and food, are suspected to be linked with several adverse health effects in humans, especially newborn babies, infants, and young children. While human exposure to parabens has been frequently reported by measuring the concentration of parabens in urine, similar measurements in breast milk have rarely been made. To determine paraben concentrations in breast milk and possible sources of exposure, four major parabens, including methylparaben (MP), ethylparaben (EP), propylparaben (PP), and butylparaben (BP) were measured in breast milk samples collected from 260 lactating women in South Korea. Demographic, socioeconomic, and behavioral factors associated with the presence of parabens in breast milk were determined. EP concentrations were detected at the highest levels in breast milk samples, followed by MP, PP, and BP. Pre-pregnancy BMI, parity, use of basic skin care products, use of cosmetics, canned beverage, and type of milk consumption were associated with higher frequencies of paraben detection. In addition, type of milk, parity, and drinking status were significantly associated with the concentration of EP. Multiple regression analyses showed that colostrum and transitional milk samples had higher levels of EP than mature milk samples. The estimated daily intake of parabens in infants via breastfeeding appears to be negligible when compared to the acceptable daily intake values set forth by the European Food Safety Authority (EFSA); however, considering the vulnerability of breastfed infants and ubiquitous sources of exposure from daily use of household and personal toiletries, efforts to identify sources and mitigate exposure are warranted. © 2019 Elsevier LtdEP concentrations were detected at the highest levels in breast milk samples from Korean lactating women, and EP levels were significantly higher in colostrum and transitional milk than mature milk. © 2019 Elsevier Ltd-
dc.language영어-
dc.language.isoENG-
dc.publisherElsevier Ltd-
dc.titleParabens in breast milk and possible sources of exposure among lactating women in Korea-
dc.typeArticle-
dc.identifier.doi10.1016/j.envpol.2019.113142-
dc.identifier.bibliographicCitationEnvironmental Pollution, v.255, no.2-
dc.description.isOpenAccessN-
dc.identifier.wosid000498340400032-
dc.identifier.scopusid2-s2.0-85072620063-
dc.citation.number2-
dc.citation.titleEnvironmental Pollution-
dc.citation.volume255-
dc.type.docTypeArticle-
dc.publisher.location영국-
dc.subject.keywordAuthorBreast milk-
dc.subject.keywordAuthorColostrum and transitional milk-
dc.subject.keywordAuthorEthylparaben-
dc.subject.keywordAuthorParabens-
dc.subject.keywordPlusSOLID-PHASE EXTRACTION-
dc.subject.keywordPlusBISPHENOL-A-
dc.subject.keywordPlusURINARY CONCENTRATIONS-
dc.subject.keywordPlusENVIRONMENTAL PHENOLS-
dc.subject.keywordPlusPREGNANT-WOMEN-
dc.subject.keywordPlusHUMAN HEALTH-
dc.subject.keywordPlusUV FILTERS-
dc.subject.keywordPlusTRICLOSAN-
dc.subject.keywordPlusMS/MS-
dc.subject.keywordPlusCOLOSTRUM-
dc.relation.journalResearchAreaEnvironmental Sciences & Ecology-
dc.relation.journalWebOfScienceCategoryEnvironmental Sciences-
dc.description.journalRegisteredClasssci-
dc.description.journalRegisteredClassscie-
dc.description.journalRegisteredClassscopus-
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