Aldose reductase inhibition of Rosa hybrida petals and its active component, kaempferol
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Quilantang, Norman G. | - |
dc.contributor.author | Limbo, Carlo A. | - |
dc.contributor.author | Lee, Ju Sung | - |
dc.contributor.author | Jacinto, Sonia D. | - |
dc.contributor.author | Moon, Sung-Kwon | - |
dc.contributor.author | Lee, Sanghyun | - |
dc.date.available | 2020-05-18T07:21:21Z | - |
dc.date.issued | 2020-06 | - |
dc.identifier.issn | 2211-3452 | - |
dc.identifier.issn | 2211-3460 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/39680 | - |
dc.description.abstract | The aldose reductase inhibitory activity of extracts from Rosa hybrida petals was evaluated, and a bioactive flavonoid, kaempferol, was isolated from petals via bioassay-guided isolation. Kaempferol was isolated from the ethyl acetate fraction of R. hybrida and was shown to exhibit strong inhibition against aldose reductase (IC50 = 0.02 mu M). Quantitative analyses of kaempferol in R. hybrida petals, different flower parts, and different Rosa species were also performed using high-performance liquid chromatography. This study is the first to establish that R. hybrida contains kaempferol and that the light-pink petals of this edible rose species exhibit the highest content of the naturally occurring aldose reductase inhibitor. The results of this study suggested the potential role of R. hybrida petals in the treatment and management of diabetic complications via aldose reductase inhibition. | - |
dc.format.extent | 7 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | 한국원예학회 | - |
dc.title | Aldose reductase inhibition of Rosa hybrida petals and its active component, kaempferol | - |
dc.type | Article | - |
dc.identifier.doi | 10.1007/s13580-020-00232-y | - |
dc.identifier.bibliographicCitation | Horticulture, Environment, and Biotechnology, v.61, no.3, pp 601 - 607 | - |
dc.identifier.kciid | ART002595780 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000526231500001 | - |
dc.identifier.scopusid | 2-s2.0-85083455736 | - |
dc.citation.endPage | 607 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 601 | - |
dc.citation.title | Horticulture, Environment, and Biotechnology | - |
dc.citation.volume | 61 | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Analysis | - |
dc.subject.keywordAuthor | Diabetes | - |
dc.subject.keywordAuthor | HPLC-UV | - |
dc.subject.keywordAuthor | Kaempferol | - |
dc.subject.keywordAuthor | Polyol pathway | - |
dc.subject.keywordPlus | DIABETIC COMPLICATIONS | - |
dc.subject.keywordPlus | FLAVONOIDS | - |
dc.subject.keywordPlus | CONSTITUENTS | - |
dc.relation.journalResearchArea | Agriculture | - |
dc.relation.journalWebOfScienceCategory | Horticulture | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
Items in ScholarWorks are protected by copyright, with all rights reserved, unless otherwise indicated.
84, Heukseok-ro, Dongjak-gu, Seoul, Republic of Korea (06974)02-820-6194
COPYRIGHT 2019 Chung-Ang University All Rights Reserved.
Certain data included herein are derived from the © Web of Science of Clarivate Analytics. All rights reserved.
You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.