Anti-reflux Surgery Versus Proton Pump Inhibitors for Severe Gastroesophageal Reflux Disease: A Cost-Effectiveness Study in Korea
DC Field | Value | Language |
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dc.contributor.author | Park, Susan | - |
dc.contributor.author | Park, Sungsoo | - |
dc.contributor.author | Park, Joong-Min | - |
dc.contributor.author | Ryu, Soorack | - |
dc.contributor.author | Hwang, Jinseub | - |
dc.contributor.author | Kwon, Jin-Won | - |
dc.contributor.author | Seo, Kyung Won | - |
dc.date.available | 2020-08-04T04:20:45Z | - |
dc.date.issued | 2020-04 | - |
dc.identifier.issn | 2093-0879 | - |
dc.identifier.issn | 2093-0887 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/42866 | - |
dc.description.abstract | Background/Aims The economic burden for gastroesophageal reflux disease (GERD) has recently increased in Asian countries. This study investigates the cost-effectiveness between anti-reflux surgery and medication, with proton pump inhibitors (PPIs) for GERD in Korea. Methods We used a decision tree and Markov model to obtain the costs and quality-adjusted life years (QALYs) of the surgical and medical strategies. Our target cohort was the severe GERD patients aged 50 years old who required a continuous double dose of PPIs. The time horizon was 10 years and all estimates were discounted at 5% per year. The incremental cost-effectiveness ratio of the anti-reflux surgery compared with medication with PPIs was calculated. Sensitivity analyses were performed on all relevant variables. Results The cost-utility analysis indicated anti-reflux surgery was more cost-effective than medication among severe GERD patients over a 10-year period. The model predicted that the surgical strategy had a cost savings of $551 and the QALYs had a gain of 1.18 as compared with the medical strategy. The break-even point in costs of the anti-reflux surgery over the medication was estimated to be 9 years. Sensitivity analyses using the varying parameter assumptions demonstrated the robustness of the study results. Conclusions This study showed anti-reflux surgery was less expensive and more effective therapy over the PPI medication after 9 years of follow-up. This suggests the surgical strategy is a cost-effective alternative to PPI medication among patients who need long-term management for GERD in Korea. | - |
dc.format.extent | 9 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | KOREAN SOC NEUROGASTROENTEROLOGY & MOTILITY | - |
dc.title | Anti-reflux Surgery Versus Proton Pump Inhibitors for Severe Gastroesophageal Reflux Disease: A Cost-Effectiveness Study in Korea | - |
dc.type | Article | - |
dc.identifier.doi | 10.5056/jnm19188 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY, v.26, no.2, pp 215 - 223 | - |
dc.identifier.kciid | ART002584665 | - |
dc.description.isOpenAccess | Y | - |
dc.identifier.wosid | 000523266700006 | - |
dc.identifier.scopusid | 2-s2.0-85089560945 | - |
dc.citation.endPage | 223 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 215 | - |
dc.citation.title | JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY | - |
dc.citation.volume | 26 | - |
dc.identifier.url | http://www.jnmjournal.org/journal/view.html?uid=1578&vmd=Full& | - |
dc.type.docType | Article | - |
dc.publisher.location | 대한민국 | - |
dc.subject.keywordAuthor | Quality-adjusted life years | - |
dc.subject.keywordAuthor | Cost of illness | - |
dc.subject.keywordAuthor | Gastroesophageal reflux disease | - |
dc.subject.keywordAuthor | Proton pump inhibitors | - |
dc.subject.keywordPlus | LAPAROSCOPIC NISSEN FUNDOPLICATION | - |
dc.subject.keywordPlus | MEDICATION USE | - |
dc.subject.keywordPlus | FOLLOW-UP | - |
dc.subject.keywordPlus | MANAGEMENT | - |
dc.subject.keywordPlus | ESOPHAGITIS | - |
dc.subject.keywordPlus | PREVALENCE | - |
dc.subject.keywordPlus | SYMPTOMS | - |
dc.subject.keywordPlus | THERAPY | - |
dc.subject.keywordPlus | UTILITY | - |
dc.subject.keywordPlus | GUIDELINES | - |
dc.relation.journalResearchArea | Gastroenterology & Hepatology | - |
dc.relation.journalResearchArea | Neurosciences & Neurology | - |
dc.relation.journalWebOfScienceCategory | Gastroenterology & Hepatology | - |
dc.relation.journalWebOfScienceCategory | Clinical Neurology | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
dc.description.journalRegisteredClass | kci | - |
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