Surface-Enhanced Raman Scattering of Dopamine on Self-Assembled Gold Nanoparticles
DC Field | Value | Language |
---|---|---|
dc.contributor.author | An, Jeung-Hee | - |
dc.contributor.author | El-Said, Waleed Ahmed | - |
dc.contributor.author | Yea, Cheol-Heon | - |
dc.contributor.author | Kim, Tae-Hyung | - |
dc.contributor.author | Choi, Jeong-Woo | - |
dc.date.available | 2020-11-16T05:59:22Z | - |
dc.date.issued | 2011-05 | - |
dc.identifier.issn | 1533-4880 | - |
dc.identifier.issn | 1533-4899 | - |
dc.identifier.uri | https://scholarworks.bwise.kr/cau/handle/2019.sw.cau/43496 | - |
dc.description.abstract | Dopamine, a potent neurotransmitter in the brain, influences a variety of motivated behaviors and plays a major role in Parkinson's disease. In this study, the Raman signal of dopamine was detected on a fabricated nanoparticle-immobilized glass surface by surface-enhanced raman spectroscopy (SERS). Amine-modified glass was prepared by the self-assembly of amine-terminated silane on substrate, followed by the deposition of gold nanoparticles. The gold nanoparticles deposited on the glass surface were functionalized by anti-dopamine or dopamine. The antigen-dopamine was captured by antibody-assembled gold substrate and detected by SERS. The optical properties and morpology of the glass substrate with immobilized gold nanoparticles were analyzed by scanning electron microscopy and UV-VIS absorption spectroscopy. The Raman spectrum of dopamine displayed broad bands at 1267, 1331, 1158, 1478, 1578 and 1584 cm(-1). The strongest peaks in the spectra (at 1267 and 1478 cm(-1)) were identified as phenolic carbon-oxygen and phenyl C=C stretches, respectively. A working curve of the SERS signal constructed from cathecol ring vibration versus antigen-dopamine concentration was obtained at 1478 cm(-1), and the non-optimized detection limit for anti-dopamine surface antigen was as low as 1 ng/ml. These results suggest that SERS-based immunosensor can be a promising tool for the detection and screening of neurotransmitters. | - |
dc.format.extent | 6 | - |
dc.language | 영어 | - |
dc.language.iso | ENG | - |
dc.publisher | AMER SCIENTIFIC PUBLISHERS | - |
dc.title | Surface-Enhanced Raman Scattering of Dopamine on Self-Assembled Gold Nanoparticles | - |
dc.type | Article | - |
dc.identifier.doi | 10.1166/jnn.2011.3688 | - |
dc.identifier.bibliographicCitation | JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY, v.11, no.5, pp 4424 - 4429 | - |
dc.description.isOpenAccess | N | - |
dc.identifier.wosid | 000290692400108 | - |
dc.identifier.scopusid | 2-s2.0-80051593054 | - |
dc.citation.endPage | 4429 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 4424 | - |
dc.citation.title | JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY | - |
dc.citation.volume | 11 | - |
dc.type.docType | Article; Proceedings Paper | - |
dc.publisher.location | 미국 | - |
dc.subject.keywordAuthor | Surface-Enhanced Raman Spectroscopy | - |
dc.subject.keywordAuthor | Dopamine | - |
dc.subject.keywordAuthor | Gold Nanoparticles | - |
dc.subject.keywordAuthor | Anti-Dopamine | - |
dc.subject.keywordAuthor | Immunosensor | - |
dc.subject.keywordPlus | NEUROTRANSMITTERS | - |
dc.subject.keywordPlus | SPECTROSCOPY | - |
dc.subject.keywordPlus | COMPOSITE | - |
dc.subject.keywordPlus | RELEASE | - |
dc.subject.keywordPlus | IMMUNOASSAY | - |
dc.subject.keywordPlus | FABRICATION | - |
dc.subject.keywordPlus | MOLECULES | - |
dc.subject.keywordPlus | ELECTRODE | - |
dc.subject.keywordPlus | CELLS | - |
dc.relation.journalResearchArea | Chemistry | - |
dc.relation.journalResearchArea | Science & Technology - Other Topics | - |
dc.relation.journalResearchArea | Materials Science | - |
dc.relation.journalResearchArea | Physics | - |
dc.relation.journalWebOfScienceCategory | Chemistry, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Nanoscience & Nanotechnology | - |
dc.relation.journalWebOfScienceCategory | Materials Science, Multidisciplinary | - |
dc.relation.journalWebOfScienceCategory | Physics, Applied | - |
dc.relation.journalWebOfScienceCategory | Physics, Condensed Matter | - |
dc.description.journalRegisteredClass | sci | - |
dc.description.journalRegisteredClass | scie | - |
dc.description.journalRegisteredClass | scopus | - |
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